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TMPRSS3 Products

(Transmembrane Protease, Serine 3 (TMPRSS3))
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, an LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor-associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012].

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Featured TMPRSS3 Categories

TMPRSS3 Antibodies

High quality antibodies with extensive validation data.

TMPRSS3 ELISA Kits

Reliable ELISA kits for a wide range of species.

TMPRSS3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TMPRSS3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
Cat. No. ABIN6265620
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB
Validations
  • (1)
  • (3)
Cat. No. ABIN2787338
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (2)
Cat. No. ABIN7180269
Quantity 100 μL
Datasheet Datasheet

Recommended TMPRSS3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648100
Quantity 96 tests
Datasheet Datasheet

Recommended TMPRSS3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
Cat. No. ABIN7509467
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3114023
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3126290
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TMPRSS3 products

Guerrero, Wang, Bachvarova, Gregoire, Renaud, Plante, Bachvarov: "A novel genome-based approach correlates TMPRSS3 overexpression in ovarian cancer with DNA hypomethylation." in: Gynecologic oncology, Vol. 125, Issue 3, pp. 720-6, (2012) (PubMed).

Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

Lee, Park, Kim, Park: "Pathogenic mutations but not polymorphisms in congenital and childhood onset autosomal recessive deafness disrupt the proteolytic activity of TMPRSS3." in: Journal of medical genetics, Vol. 40, Issue 8, pp. 629-31, (2003) (PubMed).

Synonyms and alternative names related to TMPRSS3

transmembrane protease, serine 3 (TMPRSS3), transmembrane protease, serine 3 (Tmprss3), DFNB8, DFNB10, DKFZp469L1528, ECHOS1, TADG12, TMPRSS3

Protein level used designations for TMPRSS3

  • transmembrane protease, serine 3
  • transmembrane protease serine 3-like
  • serine protease TADG-12
  • transmembrane protease serine 3
  • tumor-associated differentially-expressed gene 12 protein
  • transmembrane proteinase serine 3
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