TMED10 Products
(Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))
Categories
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq, Jul 2008].
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Featured TMED10 Categories
TMED10 Antibodies
High quality antibodies with extensive validation data.
TMED10 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TMED10 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
- (2)
Cat. No.
ABIN1386483
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF, FACS
Validations
- (2)
Cat. No.
ABIN190858
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN1536747
Quantity
400 μL
Datasheet
Datasheet
Recommended TMED10 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN6387259
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2132195
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our TMED10 products
: "TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity." in: Nature, Vol. 440, Issue 7088, pp. 1208-12, (2006) (PubMed).: "Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2." in: Journal of neuroscience research, Vol. 77, Issue 3, pp. 309-22, (2004) (PubMed).
: "The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease." in: Trends in cell biology, Vol. 8, Issue 11, pp. 447-53, (1999) (PubMed).
Synonyms and alternative names related to TMED10
transmembrane p24 trafficking protein 10 L homeolog (tmed10.L), transmembrane p24 trafficking protein 10 (TMED10), transmembrane p24 trafficking protein 10 (Tmed10), transmembrane p24 trafficking protein 10 (tmed10), 1110014C03Rik, fe06g04, p23, P24(DELTA), p24delta1, S31I125, S31III125, Tmp-21-I, tmp21, TMP21, Tmp21, wu:fb98e10, wu:fe06g04, zgc:85681Protein level used designations for TMED10
- transmembrane protein tmp21
- 21 kDa transmembrane trafficking protein
- 21 kDa transmembrane-trafficking protein
- p24 family protein delta-1
- p24delta
- p24delta1
- transmembrane emp24 domain-containing protein 10
- transmembrane protein Tmp21
- transmembrane trafficking protein
- integral membrane protein Tmp21-I (p23)
- transmembrane trafficking protein 21
- p24 delta 1
- integral membrane protein p23
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