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TLR5 Products

(Toll-Like Receptor 5 (TLR5))
This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.[provided by RefSeq, Dec 2009].

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Featured TLR5 Categories

TLR5 Antibodies

High quality antibodies with extensive validation data.

TLR5 ELISA Kits

Reliable ELISA kits for a wide range of species.

TLR5 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TLR5 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7444148
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, ICC, IHC (p), IHC (fro)
Validations
  • (5)
Cat. No. ABIN7438082
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7438379
Quantity 100 μL
Datasheet Datasheet

Recommended TLR5 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (5)
Cat. No. ABIN6730957
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970744
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1161923
Quantity 96 tests
Datasheet Datasheet

Recommended TLR5 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Mammalian Cells
Validations
  • (2)
Cat. No. ABIN7538553
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322880
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322882
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our TLR5 products

Haeggblom, Näsman, Ramqvist, Haglund, Hagström, Mäkitie, Dalianis: "TLR5 and TLR7 are differentially expressed in human papillomavirus-positive and negative base of tongue squamous cell carcinoma, and TLR7 may have an independent prognostic influence." in: Acta oto-laryngologica, Vol. 139, Issue 2, pp. 206-210, (2019) (PubMed).

Kapelouzou, Kontogiannis, Tsilimigras, Georgiopoulos, Kaklamanis, Tsourelis, Cokkinos: "Differential expression patterns of Toll Like Receptors and Interleukin-37 between calcific aortic and mitral valve cusps in humans." in: Cytokine, Vol. 116, pp. 150-160, (2019) (PubMed).

Ruuskanen, Leivo, Minn, Vahlberg, Haglund, Hagström, Irjala: "Expression of toll-like receptors in non-endemic nasopharyngeal carcinoma." in: BMC cancer, Vol. 19, Issue 1, pp. 624, (2019) (PubMed).

Kylmä, Jouhi, Listyarifah, Mohamed, Mäkitie, Remes, Haglund, Atula, Nieminen, Sorsa, Hagström: "Treponema denticola chymotrypsin-like protease as associated with HPV-negative oropharyngeal squamous cell carcinoma." in: British journal of cancer, Vol. 119, Issue 1, pp. 89-95, (2018) (PubMed).

Petes, Odoardi, Plater, Martin, Gee: "IL-27 amplifies cytokine responses to Gram-negative bacterial products and Salmonella typhimurium infection." in: Scientific reports, Vol. 8, Issue 1, pp. 13704, (2018) (PubMed).

Na, Hoang, Kim: "Hsp90 Inhibition Reduces TLR5 Surface Expression and NF-κB Activation in Human Myeloid Leukemia THP-1 Cells." in: BioMed research international, Vol. 2018, pp. 4319369, (2018) (PubMed).

Larsson, Tengroth, Xu, Uddman, Kumlien Georén, Cardell: "Substance P represents a novel first-line defense mechanism in the nose." in: The Journal of allergy and clinical immunology, (2017) (PubMed).

Li, Yu, Li, Liu, Jiao, Song, Lv, Qin: "Phycocyanin attenuates pulmonary fibrosis via the TLR2-MyD88-NF-κB signaling pathway." in: Scientific reports, Vol. 7, Issue 1, pp. 5843, (2017) (PubMed).

Huhta, Helminen, Kauppila, Salo, Porvari, Saarnio, Lehenkari, Karttunen: "The Expression of Toll-like Receptors in Normal Human and Murine Gastrointestinal Organs and the Effect of Microbiome and Cancer." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 64, Issue 8, pp. 470-82, (2017) (PubMed).

Liu, Chen, Wu, Cao, Xue, Yao, Evans-Marin, Li, Cong: "TLR5 mediates CD172α(+) intestinal lamina propria dendritic cell induction of Th17 cells." in: Scientific reports, Vol. 6, pp. 22040, (2016) (PubMed).

Synonyms and alternative names related to TLR5

toll like receptor 5 (TLR5), toll-like receptor 5 (Tlr5), toll like receptor 5 L homeolog (tlr5.L), toll-like receptor 5 (tlr-5), toll-like receptor 5b (tlr5b), SLEB1, sleb1, TIL3, til3, TLR-5, tlr-5, tlr5

Protein level used designations for TLR5

  • toll/interleukin-1 receptor-like protein 3
  • toll-like receptor 5
  • TLR 5
  • toll-like receptor 5b
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