TLR2 Products
(Toll-Like Receptor 2 (TLR2))
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The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. [provided by RefSeq, Jul 2008].
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Featured TLR2 Categories
TLR2 Antibodies
High quality antibodies with extensive validation data.
Recommended TLR2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC, ELISA
Validations
- (5)
Cat. No.
ABIN3029165
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, FACS, ELISA
Validations
- (5)
Cat. No.
ABIN3029164
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7437772
Quantity
20 μL
Datasheet
Datasheet
Recommended TLR2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7496150
Quantity
200 μg
Datasheet
Datasheet
Latest Publications for our TLR2 products
: "TLR4-Mediated Placental Pathology and Pregnancy Outcome in Experimental Malaria." in: Scientific reports, Vol. 7, Issue 1, pp. 8623, (2019) (PubMed).: "Immunohistochemical localization of TLR2 and CD14 in gingival tissue of healthy individuals and patients with chronic periodontitis." in: Biotechnic & histochemistry : official publication of the Biological Stain Commission, Vol. 92, Issue 7, pp. 487-497, (2019) (PubMed).
: "Toll-like receptor 10 (TLR10) exhibits suppressive effects on inflammation of prostate epithelial cells." in: Asian journal of andrology, (2019) (PubMed).
: "Role of whole saliva in the efficacy of sublingual immunotherapy in seasonal allergic rhinitis." in: Allergology international : official journal of the Japanese Society of Allergology, Vol. 68, Issue 1, pp. 82-89, (2019) (PubMed).
: "CD89 Is a Potent Innate Receptor for Bacteria and Mediates Host Protection from Sepsis." in: Cell reports, Vol. 27, Issue 3, pp. 762-775.e5, (2019) (PubMed).
: "Toll-like receptors blocking restores in vitro microbicidal activity in latent tuberculosis-infected subjects." in: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, Vol. 23, Issue 2, pp. 212-218, (2019) (PubMed).
: "Oxidative Stress Induces Expression of the Toll-Like Receptors (TLRs) 2 and 4 in the Human Peripheral Blood Mononuclear Cells: Implications for Metabolic Inflammation." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 53, Issue 1, pp. 1-18, (2019) (PubMed).
: "Phenotypic analysis of monocytes and CD4+ T cells in hepatitis E patients with or without pregnancy." in: Human immunology, (2019) (PubMed).
: "TRIM58 Restrains Intestinal Mucosal Inflammation by Negatively Regulating TLR2 in Myeloid Cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 203, Issue 6, pp. 1636-1649, (2019) (PubMed).
: "Glaucocalyxin B Alleviates Lipopolysaccharide-Induced Parkinson's Disease by Inhibiting TLR/NF-κB and Activating Nrf2/HO-1 Pathway." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 44, Issue 6, pp. 2091-2104, (2018) (PubMed).
Synonyms and alternative names related to TLR2
toll like receptor 2 (TLR2), toll-like receptor 2 (Tlr2), toll like receptor 2 (Tlr2), toll-like receptor 2 (tlr2), CD282, Ly105, TIL4Protein level used designations for TLR2
- toll/interleukin 1 receptor-like 4
- toll/interleukin-1 receptor-like protein 4
- toll-like receptor 2 variant 1
- toll-like receptor 2 variant 2
- Toll-like receptor 2-like protein
- TIR2
- toll-like receptor 2
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