TLE1 Products
(Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))
Categories
Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
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Featured TLE1 Categories
TLE1 Antibodies
High quality antibodies with extensive validation data.
TLE1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TLE1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse, Rat
Application
IHC, IF
Validations
- (6)
Cat. No.
ABIN7075961
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF, FACS, IHC (p)
Validations
- (22)
Cat. No.
ABIN1491049
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF, FACS, IHC (p)
Validations
- (21)
Cat. No.
ABIN1491050
Quantity
100 μL
Datasheet
Datasheet
Recommended TLE1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6232775
Quantity
96 tests
Datasheet
Datasheet
Recommended TLE1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125453
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322833
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3095909
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our TLE1 products
: "HDAC and Proteasome Inhibitors Synergize to Activate Pro-Apoptotic Factors in Synovial Sarcoma." in: PLoS ONE, Vol. 12, Issue 1, pp. e0169407, (2017) (PubMed).: "Identification of cytotoxic agents disrupting synovial sarcoma oncoprotein interactions by proximity ligation assay." in: Oncotarget, Vol. 7, Issue 23, pp. 34384-94, (2016) (PubMed).
: "Transducin-like enhancer of Split-1 (TLE1) combines with Forkhead box protein G1 (FoxG1) to promote neuronal survival." in: The Journal of biological chemistry, Vol. 287, Issue 18, pp. 14749-59, (2012) (PubMed).
: "NK-like homeodomain proteins activate NOTCH3-signaling in leukemic T-cells." in: BMC cancer, Vol. 9, pp. 371, (2009) (PubMed).
Synonyms and alternative names related to TLE1
transducin like enhancer of split 1 (TLE1), transducin-like enhancer protein 1 (Smp_150080), transducin-like enhancer of split 1 (Tle1), transducin like enhancer of split 1 (Tle1), transducin-like enhancer protein 1 (LOC100354911), transducin-like enhancer protein 1 (LOC100524475), transducin-like enhancer protein 1 (LOC100061341), transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) (TLE1), C230057C06Rik, ESG, ESG1, Estm14, GRG1, Grg1, TLE1, Tle4lProtein level used designations for TLE1
- e(Sp1) homolog
- enhancer of split groucho 1
- enhancer of split groucho-like protein 1
- transducin-like enhancer of split 1, homolog of Drosophila E(sp1)
- transducin-like enhancer protein 1
- grg-1
- groucho-related protein 1
- transducin-like enhancer of split 4 (homolog of Drosophila E(spl)) - like
- transducin-like enhancer of split 1
- transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
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