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TK2 Products

(Thymidine Kinase 2, Mitochondrial (TK2))

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This gene encodes a deoxyribonucleoside kinase that specifically phosphorylates thymidine, deoxycytidine, and deoxyuridine. The encoded enzyme localizes to the mitochondria and is required for mitochondrial DNA synthesis. Mutations in this gene are associated with a myopathic form of mitochondrial DNA depletion syndrome. Alternate splicing results in multiple transcript variants encoding distinct isoforms, some of which lack transit peptide, so are not localized to mitochondria. [provided by RefSeq, Dec 2012].

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Featured TK2 Categories

TK2 Antibodies

High quality antibodies with extensive validation data.

TK2 ELISA Kits

Reliable ELISA kits for a wide range of species.

Recommended TK2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (1)
Cat. No. ABIN1882141
Quantity 400 μL
Datasheet Datasheet

Recommended TK2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970657
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN585681
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6208151
Quantity 96 tests
Datasheet Datasheet

Recommended TK2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125383
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our TK2 products

Di Cresce, Figueredo, Rytelewski, Maleki Vareki, Way, Ferguson, Vincent, Koropatnick: "siRNA knockdown of mitochondrial thymidine kinase 2 (TK2) sensitizes human tumor cells to gemcitabine." in: Oncotarget, Vol. 6, Issue 26, pp. 22397-409, (2015) (PubMed).

Synonyms and alternative names related to TK2

thymidine kinase 2, mitochondrial (TK2), thymidine kinase 2, mitochondrial (Tk2), thymidine kinase 2, mitochondrial S homeolog (tk2.S), thymidine kinase 2, mitochondrial (tk2), AU024611, mt-TK, MTDPS2, MTTK, tk2, zgc:100948

Protein level used designations for TK2

  • mt-TK
  • thymidine kinase 2, mitochondrial
  • putative deoxyribonucleoside kinase
  • thymidine kinase 2, mitochondrial S homeolog
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