TIMP1 Products
(TIMP Metallopeptidase Inhibitor 1 (TIMP1))
Categories
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008].
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Featured TIMP1 Categories
TIMP1 Antibodies
High quality antibodies with extensive validation data.
TIMP1 ELISA Kits
Reliable ELISA kits for a wide range of species.
TIMP1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TIMP1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rabbit, Rat
Application
WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro)
Validations
- (9)
- (4)
Cat. No.
ABIN668331
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), FACS, IF
Validations
- (5)
Cat. No.
ABIN655149
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), FACS, IF
Validations
- (1)
- (4)
Cat. No.
ABIN390664
Quantity
400 μL
Datasheet
Datasheet
Recommended TIMP1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (2)
- (1)
Cat. No.
ABIN365420
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (6)
- (1)
Cat. No.
ABIN6959987
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (4)
- (1)
Cat. No.
ABIN6959986
Quantity
96 tests
Datasheet
Datasheet
Recommended TIMP1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275738
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275742
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322788
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our TIMP1 products
: "Plasma Matrix Metalloproteinase-9 and Tissue Inhibitor of Matrix Metalloproteinase-1 as Prognostic Biomarkers in Critically Ill Patients." in: Open medicine (Warsaw, Poland), Vol. 15, pp. 50-56, (2020) (PubMed).: "Biomarkers Facilitate the Assessment of Prognosis in Critically Ill Patients with Primary Brain Injury: A Cohort Study." in: International journal of environmental research and public health, Vol. 17, Issue 12, (2020) (PubMed).
: "Dominative role of MMP-14 over MMP-15 in human urinary bladder carcinoma on the basis of its enhanced specific activity." in: Medicine, Vol. 99, Issue 7, pp. e19224, (2020) (PubMed).
: "Infection of Mycobacterium tuberculosis Promotes Both M1/M2 Polarization and MMP Production in Cigarette Smoke-Exposed Macrophages." in: Frontiers in immunology, Vol. 11, pp. 1902, (2020) (PubMed).
: "The MiR-495/Annexin A3/P53 Axis Inhibits the Invasion and EMT of Colorectal Cancer Cells." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 44, Issue 5, pp. 1882-1895, (2018) (PubMed).
: "Crucial factors of the inflammatory microenvironment (IL-1β/TNF-α/TIMP-1) promote the maintenance of the malignant hemopoietic clone of myelofibrosis: an in vitro study." in: Oncotarget, Vol. 7, Issue 28, pp. 43974-43988, (2018) (PubMed).
: "The tissue inhibitor of metalloproteinases-1 (TIMP-1) promotes survival and migration of acute myeloid leukemia cells through CD63/PI3K/Akt/p21 signaling." in: Oncotarget, Vol. 8, Issue 2, pp. 2261-2274, (2018) (PubMed).
: "Gaseous signalling molecule SO2 via Hippo‑MST pathway to improve myocardial fibrosis of diabetic rats." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 8953-8963, (2018) (PubMed).
"Retraction: Naringin Alleviates Diabetic Kidney Disease through Inhibiting Oxidative Stress and Inflammatory Reaction." in: PLoS ONE, Vol. 13, Issue 2, pp. e0192465, (2018) (PubMed).
: "Hydrogen sulfide alleviates myocardial fibrosis in mice with alcoholic cardiomyopathy by downregulating autophagy." in: International journal of molecular medicine, Vol. 40, Issue 6, pp. 1781-1791, (2018) (PubMed).
Synonyms and alternative names related to TIMP1
TIMP metallopeptidase inhibitor 1 (TIMP1), TIMP metallopeptidase inhibitor 1 (Timp1), tissue inhibitor of metalloproteinase 1 (Timp1), CLGI, Clgi, DKFZp468A0912, EPA, EPO, HCI, TIMP, Timp, TIMP-1, TIMP1Protein level used designations for TIMP1
- tissue inhibitor of matrix metalloproteinase-1
- TIMP metallopeptidase inhibitor 1
- Metalloproteinase inhibitor 1
- TIMP-1
- collagenase inhibitor
- erythroid potentiating activity
- erythroid-potentiating activity
- fibroblast collagenase inhibitor
- metalloproteinase inhibitor 1
- tissue inhibitor of metalloproteinases 1
- EG-1
- embryogenin-1
- tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor)
- tissue inhibitor of metallopeptidase 1
- tissue inhibitor of metalloproteinase 1
- metalloproteinase tissue inhibitor
- metalloproteinase tissue inhibitor 1
- EPA
- TPA-S1
- TPA-induced protein
- collagenase inhibitor 16C8 fibroblast
- tissue inhibitor of metalloproteinase-1
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