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TIMD4 Products

(T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))
Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Involved in regulating T-cell proliferation and lymphotoxin signaling. Ligand for HAVCR1/TIMD1.

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Featured TIMD4 Categories

TIMD4 Antibodies

High quality antibodies with extensive validation data.

TIMD4 ELISA Kits

Reliable ELISA kits for a wide range of species.

TIMD4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TIMD4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (2)
Cat. No. ABIN7171341
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (5)
  • (1)
Cat. No. ABIN1881886
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN214525
Quantity 0.05 mg
Datasheet Datasheet

Recommended TIMD4 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6973567
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959840
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959841
Quantity 96 tests
Datasheet Datasheet

Recommended TIMD4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275735
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275733
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7320296
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our TIMD4 products

Gu, Sims, Krendelchtchikov, Tabengwa, Matthews: "Differential binding of the HIV-1 envelope to phosphatidylserine receptors." in: Biochimica et biophysica acta. Biomembranes, Vol. 1859, Issue 10, pp. 1962-1966, (2017) (PubMed).

Chen, He, Lu, Zhou, Fang, Liu, Xu: "Increased Expression of T Cell Immunoglobulin and Mucin Domain 4 Is Positively Associated with the Disease Severity of Patients with Ankylosing Spondylitis." in: Inflammation, (2014) (PubMed).

Dorfman, Hornick, Shahsafaei, Freeman: "The phosphatidylserine receptors, T cell immunoglobulin mucin proteins 3 and 4, are markers of histiocytic sarcoma and other histiocytic and dendritic cell neoplasms." in: Human pathology, Vol. 41, Issue 10, pp. 1486-94, (2010) (PubMed).

Zhao, Xu, Wang, Liang, Qi, Liu, Guo, Zhang, Ma, Gao: "Increased expression of human T-cell immunoglobulin- and mucin-domain-containing molecule-4 in peripheral blood mononuclear cells from patients with system lupus erythematosus." in: Cellular & molecular immunology, Vol. 7, Issue 2, pp. 152-6, (2010) (PubMed).

Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).

Cai, Hu, Cui, Li, Chen, Wu: "Association of TIM4 promoter polymorphism -1419G>A with childhood asthma in a Chinese Han population." in: Tissue antigens, Vol. 74, Issue 1, pp. 11-6, (2009) (PubMed).

Park, Hochreiter-Hufford, Ravichandran: "The phosphatidylserine receptor TIM-4 does not mediate direct signaling." in: Current biology : CB, Vol. 19, Issue 4, pp. 346-51, (2009) (PubMed).

Nakayama, Akiba, Takeda, Kojima, Hashiguchi, Azuma, Yagita, Okumura: "Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation." in: Blood, Vol. 113, Issue 16, pp. 3821-30, (2009) (PubMed).

Meyers, Sabatos, Chakravarti, Kuchroo: "The TIM gene family regulates autoimmune and allergic diseases." in: Trends in molecular medicine, Vol. 11, Issue 8, pp. 362-9, (2005) (PubMed).

Meyers, Chakravarti, Schlesinger, Illes, Waldner, Umetsu, Kenny, Zheng, Umetsu, DeKruyff, Strom, Kuchroo: "TIM-4 is the ligand for TIM-1, and the TIM-1-TIM-4 interaction regulates T cell proliferation." in: Nature immunology, Vol. 6, Issue 5, pp. 455-64, (2005) (PubMed).

Synonyms and alternative names related to TIMD4

T-cell immunoglobulin and mucin domain containing 4 (Timd4), T-cell immunoglobulin and mucin domain containing 4 (TIMD4), T-cell immunoglobulin and mucin domain containing 4 L homeolog (timd4.L), T cell immunoglobulin and mucin domain containing 4 (Timd4), B430010N18Rik, MGC99322, RGD1564516, SMUCKLER, TIM-4, Tim4, TIM4, TIMD4

Protein level used designations for TIMD4

  • T-cell immunoglobulin and mucin domain containing 4
  • T-cell immunoglobulin and mucin domain-containing protein 4
  • T-cell membrane protein 4
  • TIMD-4
  • smuckler
  • spleen, mucin-containing, knockout of lymphotoxin protein
  • TIM-4
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