TIM3 Products
(Hepatitis A Virus Cellular Receptor 2 (TIM 3))
Categories
The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011].
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Featured TIM3 Categories
TIM3 Antibodies
High quality antibodies with extensive validation data.
TIM3 ELISA Kits
Reliable ELISA kits for a wide range of species.
TIM3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TIM3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, FACS, ELISA, IF
Validations
- (8)
Cat. No.
ABIN185571
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, Coat, StM
Validations
- (5)
Cat. No.
ABIN6940963
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (5)
- (3)
Cat. No.
ABIN1881402
Quantity
400 μL
Datasheet
Datasheet
Recommended TIM3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956490
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956491
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN5692220
Quantity
96 tests
Datasheet
Datasheet
Recommended TIM3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275736
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN6961103
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275739
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our TIM3 products
: "Identification of Human Single-Domain Antibodies against SARS-CoV-2." in: Cell host & microbe, (2020) (PubMed).: "sTim-3 alleviates liver injury via regulation of the immunity microenvironment and autophagy." in: Cell death discovery, Vol. 6, pp. 62, (2020) (PubMed).
: "Self-Assembled Multivalent Aptamer Nanoparticles with Potential CAR-like Characteristics Could Activate T Cells and Inhibit Melanoma Growth." in: Molecular therapy oncolytics, Vol. 17, pp. 9-20, (2020) (PubMed).
: "Proteomic analysis detects deregulated reverse cholesterol transport in human subjects with ST-segment elevation myocardial infarction." in: Journal of proteomics, Vol. 222, pp. 103796, (2020) (PubMed).
: "Microtubule-Driven Stress Granule Dynamics Regulate Inhibitory Immune Checkpoint Expression in T Cells." in: Cell reports, Vol. 26, Issue 1, pp. 94-107.e7, (2019) (PubMed).
: "Transcriptomic Hallmarks of Tumor Plasticity and Stromal Interactions in Brain Metastasis." in: Cell reports, Vol. 27, Issue 4, pp. 1277-1292.e7, (2019) (PubMed).
: "Inhibition of AKT signaling uncouples T cell differentiation from expansion for receptor-engineered adoptive immunotherapy." in: JCI insight, Vol. 2, Issue 23, (2018) (PubMed).
: "Effect of IL-7 Therapy on Phospho-Ribosomal Protein S6 and TRAF1 Expression in HIV-Specific CD8 T Cells in Patients Receiving Antiretroviral Therapy." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 2, pp. 558-564, (2018) (PubMed).
: "Phase I trial of plerixafor combined with decitabine in newly diagnosed older patients with acute myeloid leukemia." in: Haematologica, Vol. 103, Issue 8, pp. 1308-1316, (2018) (PubMed).
: "Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1 c259T Cells in Synovial Sarcoma. ..." in: Cancer discovery, Vol. 8, Issue 8, pp. 944-957, (2018) (PubMed).
Synonyms and alternative names related to TIM3
hepatitis A virus cellular receptor 2 (HAVCR2), hepatitis A virus cellular receptor 2 (Havcr2), HAVcr-2, HAVCR2, KIM-3, MGC140131, Tim-3, TIM-3, TIM3, Tim3, tim3, TIMD-3, TIMD3, Timd3Protein level used designations for TIM3
- hepatitis A virus cellular receptor 2
- T cell immunoglobulin mucin 3
- T cell immunoglobulin mucin-3
- T-cell immunoglobulin and mucin domain-containing protein 3
- T-cell membrane protein 3
- kidney injury molecule-3
- HAVcr-2
- T-cell immunoglobulin and mucin domain containing 3
- TIMD-3
- hepatitis A virus cellular receptor 2 homolog
- TIM-3
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