TIGIT Products
(T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))
Categories
This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity\; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009].
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Featured TIGIT Categories
TIGIT Antibodies
High quality antibodies with extensive validation data.
TIGIT ELISA Kits
Reliable ELISA kits for a wide range of species.
TIGIT Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TIGIT Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ICC, IP
Validations
- (5)
Cat. No.
ABIN7439486
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS
Validations
- (4)
Cat. No.
ABIN7193227
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, FACS, Coat, StM
Validations
- (4)
Cat. No.
ABIN6939305
Quantity
100 μg
Datasheet
Datasheet
Recommended TIGIT ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959836
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4884793
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6730832
Quantity
96 tests
Datasheet
Datasheet
Recommended TIGIT Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (6)
Cat. No.
ABIN7275729
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (6)
Cat. No.
ABIN7275728
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7275730
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our TIGIT products
: "Self-Assembled Multivalent Aptamer Nanoparticles with Potential CAR-like Characteristics Could Activate T Cells and Inhibit Melanoma Growth." in: Molecular therapy oncolytics, Vol. 17, pp. 9-20, (2020) (PubMed).: "Molecular and functional heterogeneity of IL-10-producing CD4+ T cells. ..." in: Nature communications, Vol. 9, Issue 1, pp. 5457, (2019) (PubMed).
: "Human M2 Macrophages Limit NK Cell Effector Functions through Secretion of TGF-β and Engagement of CD85j." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 3, pp. 1008-1015, (2018) (PubMed).
: "Suppressive IL-17A+Foxp3+and ex-Th17 IL-17AnegFoxp3+Tregcells are a source of tumour-associated Tregcells." in: Nature communications, Vol. 8, pp. 14649, (2017) (PubMed).
: "HTLV-1 bZIP Factor Impairs Anti-viral Immunity by Inducing Co-inhibitory Molecule, T Cell Immunoglobulin and ITIM Domain (TIGIT)." in: PLoS pathogens, Vol. 12, Issue 1, pp. e1005372, (2016) (PubMed).
: "Binding of the Fap2 protein of Fusobacterium nucleatum to human inhibitory receptor TIGIT protects tumors from immune cell attack. ..." in: Immunity, Vol. 42, Issue 2, pp. 344-55, (2015) (PubMed).
: "Increased expression of TIGIT on CD4+ T cells ameliorates immune-mediated bone marrow failure of aplastic anemia." in: Journal of cellular biochemistry, Vol. 115, Issue 11, pp. 1918-27, (2014) (PubMed).
: "Mouse TIGIT inhibits NK-cell cytotoxicity upon interaction with PVR." in: European journal of immunology, Vol. 43, Issue 8, pp. 2138-50, (2013) (PubMed).
Synonyms and alternative names related to TIGIT
T-cell immunoreceptor with Ig and ITIM domains (TIGIT), T cell immunoreceptor with Ig and ITIM domains (Tigit), ENSMUSG00000071552, RGD1563191, VSIG9, VSTM3, Vstm3, WUCAMProtein level used designations for TIGIT
- T-cell immunoreceptor with Ig and ITIM domains
- V-set and immunoglobulin domain containing 9
- V-set and immunoglobulin domain-containing protein 9
- V-set and transmembrane domain containing 3
- V-set and transmembrane domain-containing protein 3
- Washington University cell adhesion molecule
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