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Thyroperoxidase Products

(Thyroid Peroxidase (TPO))

Categories

This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011].

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Featured Thyroperoxidase Categories

Thyroperoxidase Antibodies

High quality antibodies with extensive validation data.

Thyroperoxidase ELISA Kits

Reliable ELISA kits for a wide range of species.

Thyroperoxidase Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Thyroperoxidase Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Rat
Application WB, IF (p)
Validations
  • (3)
Cat. No. ABIN668736
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (3)
Cat. No. ABIN950047
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN521067
Quantity 100 μg
Datasheet Datasheet

Recommended Thyroperoxidase ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6959964
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6974180
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971305
Quantity 96 tests
Datasheet Datasheet

Recommended Thyroperoxidase Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Human
Validations
  • (2)
  • (2)
Cat. No. ABIN934717
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275771
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275772
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Thyroperoxidase products

Ali, Wolfe, Mukherjee, Radford, Patel, White, Milojevic, Capretta, Nair, Brennan: "A sputum bioassay for airway eosinophilia using an eosinophil peroxidase aptamer." in: Scientific reports, Vol. 12, Issue 1, pp. 22476, (2022) (PubMed).

Rehman, Zafar, Fatima, Mohib, Sheikh: "Altered sperm parameters and subclinical hypothyroidism; A cross sectional study in Karachi, Pakistan." in: International journal of clinical practice, Vol. 74, Issue 9, pp. e13555, (2021) (PubMed).

Eick, Cepon-Robins, Devlin, Kowal, Sugiyama, Snodgrass: "Development and validation of an ELISA for a biomarker of thyroid dysfunction, thyroid peroxidase autoantibodies (TPO-Ab), in dried blood spots." in: Journal of physiological anthropology, Vol. 39, Issue 1, pp. 16, (2020) (PubMed).

Rahnama, Mahmoudi, Kazemnejad, Salehi, Ghahiri, Soltanghoraee, Vafaei, Rezaei, Zarnani: "Thyroid peroxidase in human endometrium and placenta: a potential target for anti-TPO antibodies." in: Clinical and experimental medicine, (2020) (PubMed).

Singh, Song, Kim, Chin, Ji, Lee, Lee, Yoon, Yu, Kim, Yoon, Hwang, Lee, Oh, Lee, Lee, Choi, Na, Choi, Park, Song, Kim, Lee, Cho, Jeon: "A Novel Orally Active Inverse Agonist of Estrogen-related Receptor Gamma (ERRγ), DN200434, A Booster of NIS in Anaplastic Thyroid Cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, (2019) (PubMed).

Muhanhali, Zhai, Jiang, Ai, Zhu, Ling: "Long Non-coding Antisense RNA TNRC6C-AS1 Is Activated in Papillary Thyroid Cancer and Promotes Cancer Progression by Suppressing TNRC6C Expression." in: Frontiers in endocrinology, Vol. 9, pp. 360, (2018) (PubMed).

Yaglova, Sledneva, Nazimova, Obernikhin, Yaglov: "Sex Differences in the Production of SLC5A5, Thyroid Peroxidase, and Thyroid Hormones in Pubertal Rats Exposed to Endocrine Disruptor Dichlorodiphenyltrichloroethane (DDT) during Postnatal Ontogeny." in: Bulletin of experimental biology and medicine, Vol. 164, Issue 4, pp. 430-433, (2018) (PubMed).

Festuccia, Mancini, Colapietro, Gravina, Vitale, Marampon, Delle Monache, Pompili, Cristiano, Vetuschi, Tombolini, Chen, Mehrling: "The first-in-class alkylating deacetylase inhibitor molecule tinostamustine shows antitumor effects and is synergistic with radiotherapy in preclinical models of glioblastoma." in: Journal of hematology & oncology, Vol. 11, Issue 1, pp. 32, (2018) (PubMed).

Zhou, Wang, Zhao, Liu, Zhao, Zhang, Shan, Teng: "Elevated Thyroid Peroxidase Antibody Increases Risk of Post-partum Depression by Decreasing Prefrontal Cortex BDNF and 5-HT Levels in Mice." in: Frontiers in cellular neuroscience, Vol. 10, pp. 307, (2017) (PubMed).

Kim, Oh, Youn, Na, Kang, Park, Park, Jang, Lee, Jung, Chung: "Thyroid-Related Protein Expression in the Human Thymus." in: International journal of endocrinology, Vol. 2017, pp. 8159892, (2017) (PubMed).

Synonyms and alternative names related to Thyroperoxidase

thyroid peroxidase (TPO), thyroid peroxidase (Tpo), thyroid peroxidase (tpo), thyroid peroxidase (LOC100547103), LOC100218312, MSA, msa, TDH2A, TPO, TPX, tpx, xtpo

Protein level used designations for Thyroperoxidase

  • thyroid microsomal antigen
  • thyroperoxidase
  • thyroid peroxidase
  • thyroid peroxidase-like
  • thyroid peroxidase (332 AA)
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