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Thyroid Hormone Receptor, beta Products

(Thyroid Hormone Receptor, beta (THRB))
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008].

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Featured Thyroid Hormone Receptor, beta Categories

Thyroid Hormone Receptor, beta Antibodies

High quality antibodies with extensive validation data.

Thyroid Hormone Receptor, beta ELISA Kits

Reliable ELISA kits for a wide range of species.

Thyroid Hormone Receptor, beta Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Thyroid Hormone Receptor, beta Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF, ICC, IHC (p)
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  • (4)
Cat. No. ABIN467595
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7172152
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
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  • (3)
  • (2)
Cat. No. ABIN349600
Quantity 100 μg
Datasheet Datasheet

Recommended Thyroid Hormone Receptor, beta ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959962
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648298
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative DNA-Binding ELISA
Validations
Cat. No. ABIN5648643
Quantity 96 tests
Datasheet Datasheet

Recommended Thyroid Hormone Receptor, beta Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
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Cat. No. ABIN1322721
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
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Cat. No. ABIN7415668
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3074033
Quantity 1 mg
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Latest Publications for our Thyroid Hormone Receptor, beta products

Fozzatti, Park, Zhao, Willingham, Cheng: "Oncogenic Actions of the Nuclear Receptor Corepressor (NCOR1) in a Mouse Model of Thyroid Cancer." in: PLoS ONE, Vol. 8, Issue 6, pp. e67954, (2017) (PubMed).

Dong, You, Williams, Wade, Yauk, Thomas Zoeller et al.: "Transient Maternal Hypothyroxinemia Potentiates the Transcriptional Response to Exogenous Thyroid Hormone in the Fetal Cerebral Cortex Before the Onset of Fetal Thyroid Function: A Messenger and ..." in: Cerebral cortex (New York, N.Y. : 1991), Vol. 25, Issue 7, pp. 1735-45, (2015) (PubMed).

Wang, Wei, Guan, Xue: "Triiodothyronine regulates distribution of thyroid hormone receptors by activating AMP-activated protein kinase in 3T3-L1 adipocytes and induces uncoupling protein-1 expression." in: Molecular and cellular biochemistry, Vol. 393, Issue 1-2, pp. 247-54, (2014) (PubMed).

Zhao, Zhu, Won Park, Fozzatti, Willingham, Cheng: "Role of TSH in the spontaneous development of asymmetrical thyroid carcinoma in mice with a targeted mutation in a single allele of the thyroid hormone-β receptor." in: Endocrinology, Vol. 153, Issue 10, pp. 5090-100, (2012) (PubMed).

Mascanfroni, Montesinos, Alamino, Susperreguy, Nicola, Ilarregui, Masini-Repiso, Rabinovich, Pellizas: "Nuclear factor (NF)-kappaB-dependent thyroid hormone receptor beta1 expression controls dendritic cell function via Akt signaling." in: The Journal of biological chemistry, Vol. 285, Issue 13, pp. 9569-82, (2010) (PubMed).

Iizuka, Endo, Tsubochi, Nokubi, Matsuura, Sohara: "[Massive hemoptysis due to traction bronchiectasis caused by thoracic radiotherapy 23 years earlier]" in: Kyobu geka. The Japanese journal of thoracic surgery, Vol. 61, Issue 3, pp. 226-9, (2008) (PubMed).

Kim, Park, Baek, Kim, Yoo, Park: "A newly identified insertion mutation in the thyroid hormone receptor-beta gene in a Korean family with generalized thyroid hormone resistance." in: Journal of Korean medical science, Vol. 22, Issue 3, pp. 560-3, (2007) (PubMed).

Nascimento, Dias, Nunes, Aparício, Ambrosio, Bleicher, Figueira, Santos, de Oliveira Neto, Fischer, Togashi, Craievich, Garratt, Baxter, Webb, Polikarpov: "Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function." in: Journal of molecular biology, Vol. 360, Issue 3, pp. 586-98, (2006) (PubMed).

Ambrogini, Cuppini, Ferri, Mancini, Ciaroni, Voci, Gerdoni, Gallo: "Thyroid hormones affect neurogenesis in the dentate gyrus of adult rat." in: Neuroendocrinology, Vol. 81, Issue 4, pp. 244-53, (2005) (PubMed).

Constantinou, Margarity, Valcana: "Region-specific effects of hypothyroidism on the relative expression of thyroid hormone receptors in adult rat brain." in: Molecular and cellular biochemistry, Vol. 278, Issue 1-2, pp. 93-100, (2005) (PubMed).

Synonyms and alternative names related to Thyroid Hormone Receptor, beta

thyroid hormone receptor beta (THRB), thyroid hormone receptor beta (Thrb), thyroid hormone receptor beta (thrb), thyroid hormone receptor, beta (thrb), thyroid hormone receptor, beta S homeolog (thrb.S), thyroid hormone receptor, beta L homeolog (thrb.L), C-ERBA-2, C-ERBA-BETA, C-erba-beta, c-erbAbeta, CTR BETA 2, ERBA2, fj24f03, GRTH, LOC734147, NR1A2, Nr1a2, PRTH, RATT3REC, T3Rbeta, T3rec, T3R[b], THR, THR1, thrb, THRB, THRB1, Thrb1, THRB2, Thrb2, TR-beta, TR-BETA, trb, TRbeta, TRbeta1, TR[b]1, wu:fj24f03

Protein level used designations for Thyroid Hormone Receptor, beta

  • nuclear receptor subfamily 1 group A member 2
  • oncogene ERBA2
  • thyroid hormone nuclear receptor beta variant 1
  • thyroid hormone receptor beta
  • thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
  • TR beta
  • c-erbA-2
  • c-erbA-beta
  • TRbeta1
  • thyroid hormone receptor beta 1
  • thyroid hormone receptor beta 2
  • thyroid hormone receptor beta-1
  • beta-thyroid hormone receptor
  • thyroid hormone receptor beta isoform
  • TRbeta2Delta
  • thyroid hormone receptor beta 3
  • thyroid hormone receptor beta2delta
  • thyroid hormone receptor, beta (avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 2)
  • thyroid hormone receptor beta2
  • TRbetaB
  • nuclear receptor subfamily 1 group A member 2-B
  • thyroid hormone receptor beta-B
  • TRbetaA
  • nuclear receptor subfamily 1 group A member 2-A
  • xTR
  • LOW QUALITY PROTEIN: thyroid hormone receptor beta
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