Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

THO Complex 5 Products

(THO Complex 5 (THOC5))

Categories

Component the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO complex. Regulates the expression of myeloid transcription factors CEBPA, CEBPB and GAB2 by enhancing the levels of phosphatidylinositol 3,4,5-trisphosphate. May be involved in the differentiation of granulocytes and adipocytes. Essential for hematopoietic primitive cell survival and plays an integral role in monocytic development (By similarity).

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured THO Complex 5 Categories

THO Complex 5 Antibodies

High quality antibodies with extensive validation data.

THO Complex 5 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended THO Complex 5 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7172059
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IF, ICC
Validations
  • (1)
Cat. No. ABIN6265558
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6149119
Quantity 100 μL
Datasheet Datasheet

Recommended THO Complex 5 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6207985
Quantity 96 tests
Datasheet Datasheet

Recommended THO Complex 5 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322701
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our THO Complex 5 products

Gebhardt, Habjan, Benda, Meiler, Haas, Hein, Mann, Mann, Habermann, Pichlmair: "mRNA export through an additional cap-binding complex consisting of NCBP1 and NCBP3." in: Nature communications, Vol. 6, pp. 8192, (2015) (PubMed).

Ramachandran, Tran, Klebba-Faerber, Kardinal, Whetton, Tamura: "An ataxia-telangiectasia-mutated (ATM) kinase mediated response to DNA damage down-regulates the mRNA-binding potential of THOC5." in: RNA (New York, N.Y.), Vol. 17, Issue 11, pp. 1957-66, (2011) (PubMed).

Synonyms and alternative names related to THO Complex 5

THO complex 5 (THOC5), THO complex 5 (Thoc5), THO complex 5 (thoc5), THO complex 5 S homeolog (thoc5.S), THO complex 5 L homeolog (thoc5.L), 1700060C24Rik, A430085L24Rik, C22orf19, fc54b09, Fmip, fmip, fSAP79, PK1.3, Sgk2, THOC5, thoc5, thoc5-a, thoc5-b, wu:fc54b09, zgc:56190, zgc:76912

Protein level used designations for THO Complex 5

  • Fms-interacting protein
  • NF2/meningioma region protein pK1.3
  • PP39.2
  • THO complex subunit 5 homolog
  • functional spliceosome-associated protein 79
  • hTREX90
  • placental protein 39.2
  • Fms interacting protein
  • fms-interacting protein
  • serum/glucocorticoid regulated kinase 2
  • protein C22orf19
  • THO complex 5
  • THO complex subunit 5 homolog-like
  • THO complex subunit 5 homolog B
  • THO complex subunit 5 homolog A
You are here:
Support