TGFBR2 Products
(Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))
Categories
This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008].
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Featured TGFBR2 Categories
TGFBR2 Antibodies
High quality antibodies with extensive validation data.
TGFBR2 ELISA Kits
Reliable ELISA kits for a wide range of species.
TGFBR2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TGFBR2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, IF, IHC (p)
Validations
- (1)
- (7)
Cat. No.
ABIN655799
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (6)
Cat. No.
ABIN6149084
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Human, Mouse, Rabbit, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro)
Validations
- (4)
- (3)
Cat. No.
ABIN725225
Quantity
100 μL
Datasheet
Datasheet
Recommended TGFBR2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6960105
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970806
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970807
Quantity
96 tests
Datasheet
Datasheet
Recommended TGFBR2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7275717
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7275719
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275718
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our TGFBR2 products
: "Inhibition of IL-10 and TGF-β receptors on dendritic cells enhances activation of effector T-cells to kill cholangiocarcinoma cells." in: Human vaccines & immunotherapeutics, Vol. 14, Issue 6, pp. 1423-1431, (2019) (PubMed).: "(+)-Isobicyclogermacrenal and spathulenol from Aristolochia yunnanensis alleviate cardiac fibrosis by inhibiting transforming growth factor β/small mother against decapentaplegic signaling pathway." in: Phytotherapy research : PTR, Vol. 33, Issue 1, pp. 214-223, (2019) (PubMed).
: "miR-143/145 differentially regulate hematopoietic stem and progenitor activity through suppression of canonical TGFβ signaling." in: Nature communications, Vol. 9, Issue 1, pp. 2418, (2018) (PubMed).
: "Nicousamide protects kidney podocyte by inhibiting the TGFβ receptor II phosphorylation and AGE-RAGE signaling." in: American journal of translational research, Vol. 9, Issue 1, pp. 115-125, (2017) (PubMed).
: "TGF-β contamination of purified recombinant GDF15." in: PLoS ONE, Vol. 12, Issue 11, pp. e0187349, (2017) (PubMed).
: "Aspirin Inhibits LPS-Induced Expression of PI3K/Akt, ERK, NF-κB, CX3CL1, and MMPs in Human Bronchial Epithelial Cells." in: Inflammation, Vol. 39, Issue 2, pp. 643-50, (2017) (PubMed).
: "TGF-β Signaling Regulates Cementum Formation through Osterix Expression." in: Scientific reports, Vol. 6, pp. 26046, (2016) (PubMed).
: "Clathrin light chains' role in selective endocytosis influences antibody isotype switching." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 35, pp. 9816-21, (2016) (PubMed).
: "24R,25-Dihydroxyvitamin D3 Protects against Articular Cartilage Damage following Anterior Cruciate Ligament Transection in Male Rats." in: PLoS ONE, Vol. 11, Issue 8, pp. e0161782, (2016) (PubMed).
: "TGF-β receptor maintains CD4 T helper cell identity during chronic viral infections." in: The Journal of clinical investigation, Vol. 126, Issue 10, pp. 3799-3813, (2016) (PubMed).
Synonyms and alternative names related to TGFBR2
transforming growth factor beta receptor 2 (TGFBR2), transforming growth factor, beta receptor II (Tgfbr2), transforming growth factor, beta receptor 2 (Tgfbr2), transforming growth factor beta receptor 2b (tgfbr2b), transforming growth factor beta receptor 2 (Tgfbr2), 1110020H15Rik, AAT3, AU042018, cb537, DNIIR, FAA3, LDS1B, LDS2B, MFS2, RIIC, RIIDN, TAAD2, TBETA-RII, TbetaR-II, TbetaRII, TBR-II, TGF-beta 2, TGFbeta-RII, TGFBR2, tgfbr2, Tgfbr2T, TGFBRII, TGFR-2, wu:fj05c10, zgc:110498Protein level used designations for TGFBR2
- TGF-beta receptor type II
- TGF-beta receptor type-2
- TGF-beta type II receptor
- TGFR-2
- tbetaR-II
- transforming growth factor-beta receptor type II
- transforming growth factor-beta type II receptor
- TGF-beta receptor type IIB
- transforming growth factor beta receptor type IIC
- TGF-beta receptor II
- transforming growth factor, beta receptor II (70/80kDa)
- transforming growth factor beta type II receptor
- transforming growth factor, beta receptor II
- transforming growth factor beta receptor 2
- TGF beta receptor type II
- TGF-beta receptor type-2-like
- transforming growth factor beta receptor type II
- transforming growth factor beta, receptor 2
- transforming growth factor, beta receptor 2
- transforming growth factor, beta receptor IIT
- transforming growth factor-b type II receptor
- TGF-beta receptor 2
- transforming growth factor-beta receptor 2
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