TGFBR1 Products
(Transforming Growth Factor, beta Receptor 1 (TGFBR1))
Categories
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].
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Featured TGFBR1 Categories
TGFBR1 Antibodies
High quality antibodies with extensive validation data.
TGFBR1 ELISA Kits
Reliable ELISA kits for a wide range of species.
TGFBR1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TGFBR1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (5)
Cat. No.
ABIN563176
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, ELISA, IHC, FACS
Validations
- (5)
Cat. No.
ABIN768623
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (4)
Cat. No.
ABIN7193143
Quantity
100 μg
Datasheet
Datasheet
Recommended TGFBR1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6960102
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970805
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970804
Quantity
96 tests
Datasheet
Datasheet
Recommended TGFBR1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7275720
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN6964080
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322609
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our TGFBR1 products
: "Bellidifolin Ameliorates Isoprenaline-Induced Myocardial Fibrosis by Regulating TGF-β1/Smads and p38 Signaling and Preventing NR4A1 Cytoplasmic Localization." in: Frontiers in pharmacology, Vol. 12, pp. 644886, (2021) (PubMed).: "The aqueous extract of Gentianella acuta improves isoproterenol‑induced myocardial fibrosis via inhibition of the TGF‑β1/Smads signaling pathway." in: International journal of molecular medicine, Vol. 45, Issue 1, pp. 223-233, (2020) (PubMed).
: "Lumican promotes joint fibrosis through TGF-β signaling." in: FEBS open bio, Vol. 10, Issue 11, pp. 2478-2488, (2020) (PubMed).
: "Integrated Proteomic and Transcriptomic Analysis Reveals Long Noncoding RNA HOX Transcript Antisense Intergenic RNA (HOTAIR) Promotes Hepatocellular Carcinoma Cell Proliferation by Regulating Opioid ..." in: Molecular & cellular proteomics : MCP, Vol. 17, Issue 1, pp. 146-159, (2019) (PubMed).
: "MicroRNA-98-5p inhibits proliferation and metastasis in non-small cell lung cancer by targeting TGFBR1." in: International journal of oncology, Vol. 54, Issue 1, pp. 128-138, (2019) (PubMed).
: "Ryanodine Receptor Type 2 Plays a Role in the Development of Cardiac Fibrosis under Mechanical Stretch Through TGFβ-1." in: International heart journal, Vol. 58, Issue 6, pp. 957-961, (2018) (PubMed).
: "Long non-coding RNA DILC regulates liver cancer stem cells via IL-6/STAT3 axis." in: Journal of hepatology, Vol. 64, Issue 6, pp. 1283-94, (2018) (PubMed).
: "Activation of RhoA, Smad2, c-Src, PKC-βII/δ and JNK in atopic dermatitis." in: The Australasian journal of dermatology, Vol. 59, Issue 4, pp. e258-e261, (2018) (PubMed).
: "Effect of astragalus injection on renal tubular epithelial transdifferentiation in type 2 diabetic mice." in: BMC complementary and alternative medicine, Vol. 16, pp. 222, (2017) (PubMed).
: "The Modulatory Properties of Chronic Antidepressant Drugs Treatment on the Brain Chemokine - Chemokine Receptor Network: A Molecular Study in an Animal Model of Depression." in: Frontiers in pharmacology, Vol. 8, pp. 779, (2017) (PubMed).
Synonyms and alternative names related to TGFBR1
transforming growth factor beta receptor 1 (TGFBR1), transforming growth factor beta receptor I (tgfbr1), transforming growth factor beta receptor I S homeolog (tgfbr1.S), transforming growth factor, beta receptor I (Tgfbr1), transforming growth factor, beta receptor 1 (Tgfbr1), transforming growth factor, beta receptor 1 a (tgfbr1a), AAT5, aat5, ACVRLK4, acvrlk4, ALK-5, alk-5, Alk-5, ALK5, alk5, Alk5, AU017191, LDS1A, lds1a, LDS2A, lds2a, MSSE, SKR4, skr4, Skr4, TbetaR-I, tbetaR-I, TbetaRI, TGFBR1, tgfbr1, TGFR-1, tgfr-1, Tgfr-1, x-trr1, zgc:123263Protein level used designations for TGFBR1
- TGF-beta receptor type I
- TGF-beta receptor type-1
- TGF-beta type I receptor
- activin A receptor type II-like kinase, 53kD
- activin A receptor type II-like kinase, 53kDa
- activin A receptor type II-like protein kinase of 53kD
- activin receptor-like kinase 5
- serine/threonine-protein kinase receptor R4
- tbetaR-I
- transforming growth factor beta receptor I
- transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kD)
- transforming growth factor-beta receptor type I
- transforming growth factor, beta receptor 1 (activin A receptor type II-like kinase, 53kDa)
- transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa)
- transforming growth factor beta type I receptor
- transforming growth factor, beta receptor 1
- transforming growth factor beta receptor 1
- TGFR-1
- activin A receptor type II-like kinase
- transforming growth factor beta receptor type I
- transforming growth factor beta, receptor 1
- type I serine/threonine kinase receptor
- TGF-beta receptor type-1-like
- ESK2
- transforming growth factor, beta receptor I
- alk5a
- transforming growth factor, beta receptor 1 a
- transforming growth factor, beta receptor I a
- transforming growth factor-beta receptor type I a
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