TGF-beta Products
(TGF-beta (TGFb))
Categories
This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.[provided by RefSeq, Oct 2009].
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Featured TGF-beta Categories
TGF-beta Antibodies
High quality antibodies with extensive validation data.
TGF-beta ELISA Kits
Reliable ELISA kits for a wide range of species.
TGF-beta Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TGF-beta Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rabbit, Rat, Sheep
Application
WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (2)
Cat. No.
ABIN707021
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mammalian, Mouse, Rabbit, Rat
Application
WB, ELISA, IHC (p)
Validations
- (3)
- (1)
Cat. No.
ABIN2476753
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Hamster, Human, Monkey, Mouse, Rat
Application
ELISA, Func, D, ELISA (Capture)
Validations
- (1)
Cat. No.
ABIN6940723
Quantity
100 μg
Datasheet
Datasheet
Recommended TGF-beta ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Monkey
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1059453
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Sheep
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1059454
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Chicken
Analytical Method
Competition ELISA
Validations
Cat. No.
ABIN1059452
Quantity
96 tests
Datasheet
Datasheet
Recommended TGF-beta Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Hi-5 Cells
Validations
Cat. No.
ABIN2469123
Quantity
0.002 mg
Datasheet
Datasheet
Latest Publications for our TGF-beta products
: "Plasminogen activator inhibitor-1 reduces cardiac fibrosis and promotes M2 macrophage polarization in inflammatory cardiomyopathy." in: Basic research in cardiology, Vol. 116, Issue 1, pp. 1, (2021) (PubMed).: "Marked variability in bioactivity between commercially available bovine colostrum for human use; implications for clinical trials." in: PLoS ONE, Vol. 15, Issue 6, pp. e0234719, (2020) (PubMed).
: "Gallic acid-coated sliver nanoparticle alters the expression of radiation-induced epithelial-mesenchymal transition in non-small lung cancer cells." in: Toxicology in vitro : an international journal published in association with BIBRA, Vol. 52, pp. 170-177, (2018) (PubMed).
: "Downregulation of miR-145 in venous malformations: Its association with disorganized vessels and sclerotherapy." in: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, Vol. 100, pp. 126-131, (2017) (PubMed).
: "Disorganized vascular structures in sporadic venous malformations: a possible correlation with balancing effect between Tie2 and TGF-β." in: Scientific reports, Vol. 4, pp. 5457, (2016) (PubMed).
: "Severe renal mass reduction impairs recovery and promotes fibrosis after AKI." in: Journal of the American Society of Nephrology : JASN, Vol. 25, Issue 7, pp. 1496-507, (2014) (PubMed).
: "Immunohistochemical study of tubular epithelial cells and vascular endothelial cells in glomerulonephritis." in: Renal failure, Vol. 36, Issue 8, pp. 1208-14, (2014) (PubMed).
: "Loss of monocyte chemoattractant protein-1 alters macrophage polarization and reduces NF?B activation in the foreign body response." in: Acta biomaterialia, Vol. 11, pp. 37-47, (2014) (PubMed).
: "Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and G?q-mediated Rho and ?v?6 integrin-dependent activation of TGF-?." in: The American journal of pathology, Vol. 181, Issue 4, pp. 1236-49, (2012) (PubMed).
: "Impaired STAT phosphorylation in T cells from melanoma patients in response to IL-2: association with clinical stage." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 12, pp. 4085-94, (2009) (PubMed).
Synonyms and alternative names related to TGF-beta
transforming growth factor beta 1 (TGFB1), transforming growth factor beta-1 (TGFB1), transforming growth factor beta 1 (Tgfb1), transforming growth factor, beta 1 (Tgfb1), CED, DPD1, LAP, TGF-beta, TGF-BETA-1, TGF-beta1, TGFB, Tgfb, Tgfb-1, TGFbeta, TGFbeta1Protein level used designations for TGF-beta
- TGF-beta 1 protein
- TGF-beta-1
- latency-associated peptide
- transforming growth factor beta-1
- transforming growth factor, beta 1 (Camurati-Engelmann disease)
- transforming growth factor-beta 1
- transforming growth factor beta 1
- transforming growth factor-beta
- transforming growth factor beta1
- transforming growth factor-beta-1
- TGF-beta 1
- regulatory protein
- transforming growth factor, beta-1
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