TFPI Products
(Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI))
Categories
This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed. [provided by RefSeq, Jul 2008].
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Featured TFPI Categories
TFPI Antibodies
High quality antibodies with extensive validation data.
TFPI ELISA Kits
Reliable ELISA kits for a wide range of species.
TFPI Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TFPI Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7427348
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7431728
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, IHC (p)
Validations
- (3)
Cat. No.
ABIN962011
Quantity
50 μg
Datasheet
Datasheet
Recommended TFPI ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN367608
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6960009
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (1)
Cat. No.
ABIN6960010
Quantity
96 tests
Datasheet
Datasheet
Recommended TFPI Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275696
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322583
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322581
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our TFPI products
: "Kunitz-type protease inhibitor as a vaccine candidate against schistosomiasis mansoni." in: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, Vol. 66, pp. 26-32, (2018) (PubMed).: "Extracellular vesicles from malignant effusions induce tumor cell migration: inhibitory effect of LMWH tinzaparin." in: Cell biology international, Vol. 40, Issue 10, pp. 1050-61, (2016) (PubMed).
: "Procoagulant and fibrinolytic activity after polytrauma in rat." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 310, Issue 4, pp. R323-9, (2016) (PubMed).
: "Age- and sex-specific differences in blood-borne microvesicles from apparently healthy humans." in: Biology of sex differences, Vol. 6, pp. 10, (2015) (PubMed).
: "Cathepsin G in Experimental Tuberculosis: Relevance for Antibacterial Protection and Potential for Immunotherapy." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 7, pp. 3325-33, (2015) (PubMed).
: "Trans-fatty acid promotes thrombus formation in mice by aggravating antithrombogenic endothelial functions via Toll-like receptors." in: Molecular nutrition & food research, Vol. 59, Issue 4, pp. 729-40, (2015) (PubMed).
: "Endothelial cell-anchored tissue factor pathway inhibitor regulates tumor metastasis to the lung in mice." in: Molecular carcinogenesis, (2015) (PubMed).
: "Target-mediated clearance and bio-distribution of a monoclonal antibody against the Kunitz-type protease inhibitor 2 domain of Tissue Factor Pathway Inhibitor." in: Thrombosis research, Vol. 133, Issue 3, pp. 464-71, (2014) (PubMed).
: "Tissue factor pathway inhibitor in paediatric patients with nephrotic syndrome." in: SAJCH : the South African journal of child health, Vol. 5, Issue 4, pp. 107-111, (2012) (PubMed).
: "Gla-domainless factor Xa: molecular bait to bypass a blocked tenase complex." in: Haematologica, Vol. 97, Issue 8, pp. 1165-72, (2012) (PubMed).
Synonyms and alternative names related to TFPI
tissue factor pathway inhibitor (TFPI), tissue factor pathway inhibitor (Tfpi), tissue factor pathway inhibitor a (tfpia), A630013F22Rik, AW552122, EPI, LACI, si:dz44f8.1, TFI, TFPI, TFPI1, tfpib, wu:fb92g01, zgc:152844, zgc:158592Protein level used designations for TFPI
- anti-convertin
- extrinsic pathway inhibitor
- tissue factor pathway inhibitor
- lipoprotein-associated coagulation inhibitor
- EPI
- LACI
- uncharacterized protein LOC100155068
- LOW QUALITY PROTEIN: tissue factor pathway inhibitor
- coagulation inhibitor
- lipoprotein-associated
- tissue factor pathway inhibitor b
- tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
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