TFF1 Products
(Trefoil Factor 1 (TFF1))
Categories
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008].
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Featured TFF1 Categories
TFF1 Antibodies
High quality antibodies with extensive validation data.
TFF1 ELISA Kits
Reliable ELISA kits for a wide range of species.
TFF1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TFF1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC, IF, FACS, StM
Validations
- (6)
Cat. No.
ABIN6940690
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (5)
Cat. No.
ABIN3015566
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC
Validations
- (4)
Cat. No.
ABIN7259749
Quantity
200 μL
Datasheet
Datasheet
Recommended TFF1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (1)
Cat. No.
ABIN6960159
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960160
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960161
Quantity
96 tests
Datasheet
Datasheet
Recommended TFF1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
Cat. No.
ABIN5509512
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275692
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275693
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our TFF1 products
: "Protective Effects of Wheat Peptides against Ethanol-Induced Gastric Mucosal Lesions in Rats: Vasodilation and Anti-Inflammation." in: Nutrients, Vol. 12, Issue 8, (2020) (PubMed).: "miR-632 promotes gastric cancer progression by accelerating angiogenesis in a TFF1-dependent manner." in: BMC cancer, Vol. 19, Issue 1, pp. 14, (2019) (PubMed).
: "Proteolytic effects of gingipains on trefoil factor family peptides." in: Clinical oral investigations, Vol. 22, Issue 2, pp. 1009-1018, (2018) (PubMed).
: "miR218-5p regulates the proliferation of gastric cancer cells by targeting TFF1 in an Erk1/2-dependent manner." in: Biochimica et biophysica acta, Vol. 1852, Issue 5, pp. 970-9, (2015) (PubMed).
: "Identification of a Three-Biomarker Panel in Urine for Early Detection of Pancreatic Adenocarcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 21, Issue 15, pp. 3512-21, (2015) (PubMed).
: "Serum trefoil factor 3 is a promising non-invasive biomarker for gastric cancer screening: a monocentric cohort study in China." in: BMC gastroenterology, Vol. 14, pp. 74, (2014) (PubMed).
: "High trefoil factor 1 (TFF1) expression in human retinoblastoma cells correlates with low growth kinetics, increased cyclin-dependent kinase (CDK) inhibitor levels and a selective down-regulation of ..." in: Histochemistry and cell biology, Vol. 139, Issue 2, pp. 323-38, (2014) (PubMed).
: "Antibody-based protein profiling of the human chromosome 21." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 3, pp. M111.013458, (2012) (PubMed).
: "Characterization of the human gastric fluid proteome reveals distinct pH-dependent protein profiles: implications for biomarker studies." in: Journal of proteome research, Vol. 10, Issue 10, pp. 4535-46, (2011) (PubMed).
: "Pathophysiological investigation of the gastric surface mucous gel layer of patients with Helicobacter pylori infection by using immunoassays for trefoil factor family 2 and gastric gland mucous ..." in: Digestive diseases and sciences, Vol. 56, Issue 12, pp. 3498-506, (2011) (PubMed).
Synonyms and alternative names related to TFF1
trefoil factor 1 (TFF1), trefoil factor 1 (Tff1), trefoil factor 1 S homeolog (tff1.S), trefoil factor 1, gene 2 S homeolog (tff1.2.S), trefoil factor 1 (LOC100358238), BCEI, Bcei, bcei, D21S21, d21s21, HP1.A, hp1.a, HPS2, hps2, p1, p1-a, pNR-2, pnr-2, pS2, PS2, ps2, Ps2, tff1, TFF1, xP1, xp1, xp1-LProtein level used designations for TFF1
- breast cancer estrogen-inducible protein
- breast cancer estrogen-inducible sequence
- gastrointestinal trefoil protein pS2
- polypeptide P1.A
- protein pS2
- P-domain peptide pS2 gene product homolog
- putative gastrointestinal growth factor xP1
- trefoil factor 1 (breast cancer, estrogen-inducible sequence expressed in)
- trefoil factor family peptide 1
- trefoil factor 1
- P-domain peptide
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