TFEC Products
(Transcription Factor EC (TFEC))
Categories
This gene encodes a member of the micropthalmia (MiT) family of basic helix-loop-helix leucine zipper transcription factors. MiT transcription factors regulate the expression of target genes by binding to E-box recognition sequences as homo- or heterodimers, and play roles in multiple cellular processes including survival, growth and differentiation. The encoded protein is a transcriptional activator of the nonmuscle myosin II heavy chain-A gene, and may also co-regulate target genes in osteoclasts as a heterodimer with micropthalmia-associated transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011].
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Featured TFEC Categories
TFEC Antibodies
High quality antibodies with extensive validation data.
TFEC Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TFEC Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
ELISA, IHC
Validations
- (3)
Cat. No.
ABIN334506
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (3)
Cat. No.
ABIN524764
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (3)
- (1)
Cat. No.
ABIN1881878
Quantity
400 μL
Datasheet
Datasheet
Recommended TFEC ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6207965
Quantity
96 tests
Datasheet
Datasheet
Recommended TFEC Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322567
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322565
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3120024
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our TFEC products
: "Oncogenic MITF dysregulation in clear cell sarcoma: defining the MiT family of human cancers." in: Cancer cell, Vol. 9, Issue 6, pp. 473-84, (2006) (PubMed).: "The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter." in: Journal of leukocyte biology, Vol. 71, Issue 2, pp. 304-10, (2002) (PubMed).
: "TFEC can function as a transcriptional activator of the nonmuscle myosin II heavy chain-A gene in transfected cells." in: Biochemistry, Vol. 40, Issue 30, pp. 8887-97, (2001) (PubMed).
: "The bHLH-Zip transcription factor Tfeb is essential for placental vascularization." in: Development (Cambridge, England), Vol. 125, Issue 23, pp. 4607-16, (1999) (PubMed).
: "Molecular cloning of cDNA encoding a human TFEC isoform, a newly identified transcriptional regulator." in: Biochimica et biophysica acta, Vol. 1353, Issue 1, pp. 23-31, (1997) (PubMed).
Synonyms and alternative names related to TFEC
transcription factor EC (tfec), transcription factor EC (TFEC), transcription factor EC (Tfec), BB107417, bHLHe34, hTFEC-L, si:ch211-238e6.5, TCFEC, Tcfec, TFE-C, TFEC, TFEC-L, TFECLProtein level used designations for TFEC
- transcription factor EC
- class E basic helix-loop-helix protein 34
- TFE-C
- mTFEC
- rTFEC
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