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TFEC Products

(Transcription Factor EC (TFEC))

Categories

This gene encodes a member of the micropthalmia (MiT) family of basic helix-loop-helix leucine zipper transcription factors. MiT transcription factors regulate the expression of target genes by binding to E-box recognition sequences as homo- or heterodimers, and play roles in multiple cellular processes including survival, growth and differentiation. The encoded protein is a transcriptional activator of the nonmuscle myosin II heavy chain-A gene, and may also co-regulate target genes in osteoclasts as a heterodimer with micropthalmia-associated transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011].

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Featured TFEC Categories

TFEC Antibodies

High quality antibodies with extensive validation data.

TFEC Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TFEC Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application ELISA, IHC
Validations
  • (3)
Cat. No. ABIN334506
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (3)
Cat. No. ABIN524764
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
  • (1)
Cat. No. ABIN1881878
Quantity 400 μL
Datasheet Datasheet

Recommended TFEC ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6207965
Quantity 96 tests
Datasheet Datasheet

Recommended TFEC Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322567
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322565
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3120024
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TFEC products

Davis, Kim, Ozsolak, Widlund, Rozenblatt-Rosen, Granter, Du, Fletcher, Denny, Lessnick, Linehan, Kung, Fisher: "Oncogenic MITF dysregulation in clear cell sarcoma: defining the MiT family of human cancers." in: Cancer cell, Vol. 9, Issue 6, pp. 473-84, (2006) (PubMed).

Mansky, Sulzbacher, Purdom, Nelsen, Hume, Rehli, Ostrowski: "The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter." in: Journal of leukocyte biology, Vol. 71, Issue 2, pp. 304-10, (2002) (PubMed).

Chung, Kim, Kawamoto: "TFEC can function as a transcriptional activator of the nonmuscle myosin II heavy chain-A gene in transfected cells." in: Biochemistry, Vol. 40, Issue 30, pp. 8887-97, (2001) (PubMed).

Steingrímsson, Tessarollo, Reid, Jenkins, Copeland: "The bHLH-Zip transcription factor Tfeb is essential for placental vascularization." in: Development (Cambridge, England), Vol. 125, Issue 23, pp. 4607-16, (1999) (PubMed).

Yasumoto, Shibahara: "Molecular cloning of cDNA encoding a human TFEC isoform, a newly identified transcriptional regulator." in: Biochimica et biophysica acta, Vol. 1353, Issue 1, pp. 23-31, (1997) (PubMed).

Synonyms and alternative names related to TFEC

transcription factor EC (tfec), transcription factor EC (TFEC), transcription factor EC (Tfec), BB107417, bHLHe34, hTFEC-L, si:ch211-238e6.5, TCFEC, Tcfec, TFE-C, TFEC, TFEC-L, TFECL

Protein level used designations for TFEC

  • transcription factor EC
  • class E basic helix-loop-helix protein 34
  • TFE-C
  • mTFEC
  • rTFEC
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