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TFB2M Products

(Transcription Factor B2, Mitochondrial (TFB2M))

Categories

S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity (By similarity).

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Featured TFB2M Categories

TFB2M Antibodies

High quality antibodies with extensive validation data.

TFB2M ELISA Kits

Reliable ELISA kits for a wide range of species.

TFB2M Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TFB2M Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (4)
Cat. No. ABIN528570
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (1)
  • (2)
Cat. No. ABIN654104
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IHC
Validations
  • (2)
Cat. No. ABIN768660
Quantity 100 μg
Datasheet Datasheet

Recommended TFB2M ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1129753
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1129754
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1129755
Quantity 96 tests
Datasheet Datasheet

Recommended TFB2M Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125446
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322543
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7279991
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our TFB2M products

Qu, Yasukawa, Kang: "Suppression of mitochondrial transcription initiation complexes changes the balance of replication intermediates of mitochondrial DNA and reduces 7S DNA in cultured human cells." in: Journal of biochemistry, Vol. 160, Issue 1, pp. 49-57, (2017) (PubMed).

Litonin, Sologub, Shi, Savkina, Anikin, Falkenberg, Gustafsson, Temiakov: "Human mitochondrial transcription revisited: only TFAM and TFB2M are required for transcription of the mitochondrial genes in vitro." in: The Journal of biological chemistry, Vol. 285, Issue 24, pp. 18129-33, (2010) (PubMed).

Falkenberg, Gaspari, Rantanen, Trifunovic, Larsson, Gustafsson: "Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA." in: Nature genetics, Vol. 31, Issue 3, pp. 289-94, (2002) (PubMed).

Synonyms and alternative names related to TFB2M

mitochondrial transcription factor B2 (mtTFB2), transcription factor B2, mitochondrial (TFB2M), transcription factor B2, mitochondrial (tfb2m), transcription factor B2, mitochondrial (Tfb2m), CG3910, d-mtTFB2, d-TF2BM, Dmel\\CG3910, hkp1, Hkp1, mtTFB2, sb:cb857, TFB2, TFB2M

Protein level used designations for TFB2M

  • CG3910-PA
  • mtTFB2-PA
  • transcription factor B2, mitochondrial
  • dimethyladenosine transferase 2, mitochondrial
  • HCV NS5A-transactivated protein 5
  • S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2
  • h-mtTFB
  • h-mtTFB2
  • hTFB2M
  • hepatitis C virus NS5A-transactivated protein 5
  • mitochondrial 12S rRNA dimethylase 2
  • mitochondrial transcription factor B2
  • mtTFB2
  • house-keeping protein 1
  • mTFB2M
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