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TFAP2A Products

(Transcription Factor AP-2 alpha (Activating Enhancer Binding Protein 2 Alpha) (TFAP2A))

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The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009].

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Featured TFAP2A Categories

TFAP2A Antibodies

High quality antibodies with extensive validation data.

TFAP2A Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TFAP2A Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, FACS, ICC
Validations
  • (7)
Cat. No. ABIN5611192
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, FACS
Validations
  • (8)
Cat. No. ABIN5542420
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS
Validations
  • (5)
Cat. No. ABIN5611193
Quantity 100 μL
Datasheet Datasheet

Recommended TFAP2A ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380925
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative DNA-Binding ELISA
Validations
Cat. No. ABIN5648531
Quantity 96 tests
Datasheet Datasheet

Recommended TFAP2A Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1322523
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125441
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322521
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our TFAP2A products

Yang, Wei, Song, Cai, Zhou, Peng, Jiang, Peng: "E4BP4 mediates glucocorticoid-regulated adipogenesis through COX2." in: Molecular and cellular endocrinology, Vol. 450, pp. 43-53, (2018) (PubMed).

Wilson, Olm-Shipman, Acevedo, Palaniyandi, Hall, Kosa, Stumpff, Smith, Pitstick, Liao, Bjork, Czirok, Saadi: "SPECC1L deficiency results in increased adherens junction stability and reduced cranial neural crest cell delamination." in: Scientific reports, Vol. 6, pp. 17735, (2016) (PubMed).

Milgrom-Hoffman, Michailovici, Ferrara, Zelzer, Tzahor: "Endothelial cells regulate neural crest and second heart field morphogenesis." in: Biology open, Vol. 3, Issue 8, pp. 679-88, (2014) (PubMed).

Van Otterloo, Li, Garnett, Cattell, Medeiros, Cornell: "Novel Tfap2-mediated control of soxE expression facilitated the evolutionary emergence of the neural crest." in: Development (Cambridge, England), Vol. 139, Issue 4, pp. 720-30, (2012) (PubMed).

Li, Xia, Huang, Chen, Su, Li, Wang, Ding, Shao: "A strategy to rapidly identify the functional targets of microRNAs by combining bioinformatics and mRNA cytoplasmic/nucleic ratios in culture cells." in: FEBS letters, Vol. 584, Issue 14, pp. 3198-202, (2010) (PubMed).

Kuckenberg, Buhl, Woynecki, van Fürden, Tolkunova, Seiffe, Moser, Tomilin, Winterhager, Schorle: "The transcription factor TCFAP2C/AP-2gamma cooperates with CDX2 to maintain trophectoderm formation." in: Molecular and cellular biology, Vol. 30, Issue 13, pp. 3310-20, (2010) (PubMed).

Wells, Rivera, Kim, Starbuck, Haber: "The predominant WT1 isoform (+KTS) encodes a DNA-binding protein targeting the planar cell polarity gene Scribble in renal podocytes." in: Molecular cancer research : MCR, Vol. 8, Issue 7, pp. 975-85, (2010) (PubMed).

Scibetta, Wong, Chan, Canosa, Hurst: "Dual association by TFAP2A during activation of the p21cip/CDKN1A promoter." in: Cell cycle (Georgetown, Tex.), Vol. 9, Issue 22, pp. 4525-32, (2010) (PubMed).

Zhang, Li, Shibahara, Takahashi: "Synergistic activation of the human adrenomedullin gene promoter by Sp1 and AP-2alpha." in: Peptides, Vol. 29, Issue 3, pp. 465-72, (2008) (PubMed).

Allouche, Nolens, Tancredi, Delacroix, Mardaga, Fridman, Winkler, Boniver, Delvenne, Begon: "The combined immunodetection of AP-2alpha and YY1 transcription factors is associated with ERBB2 gene overexpression in primary breast tumors." in: Breast cancer research : BCR, Vol. 10, Issue 1, pp. R9, (2008) (PubMed).

Synonyms and alternative names related to TFAP2A

transcription factor AP-2 alpha (TFAP2A), transcription factor AP-2 (LOC100302602), tto transcription factor AP-2 alpha (tfap2a), transcription factor AP-2 alpha (tfap2a), to transcription factor AP-2 alpha L homeolog (tfap2a.L), to transcription factor AP-2 alpha S homeolog (tfap2a.S), Transcription factor AP-2 alpha (ap2a), transcription factor AP-2, alpha (Tfap2a), transcription factor AP-2 alpha (Tfap2a), Ap-2, AP-2, AP-2alpha, ap-2alpha, ap2, Ap2, AP2, ap2a, AP2alpha, AP2TF, ap2tf, Ap2tf, BOFS, cb93, fb83f04, fc31a07, tcfap2a, Tcfap2a, TFAP2, tfap2, TFAP2A, tfap2a-a, tfap2alpha, wu:fb83f04, wu:fc31a07, XAP-2, xap2

Protein level used designations for TFAP2A

  • transcription factor AP-2 alpha
  • transcription factor AP-2
  • AP-2 transcription factor
  • AP2-alpha
  • activating enhancer-binding protein 2-alpha
  • activator protein 2
  • transcription factor AP-2-alpha
  • transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
  • ap2
  • ap2a
  • lockjaw
  • low
  • mob
  • mont blanc
  • activating enhancer-binding protein 2 alpha
  • Transcription factor AP-2 alpha
  • AP-2 alpha
  • Ap-2 (a)
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