TET2 Products
(Tet Methylcytosine Dioxygenase 2 (TET2))
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The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011].
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Featured TET2 Categories
TET2 Antibodies
High quality antibodies with extensive validation data.
TET2 ELISA Kits
Reliable ELISA kits for a wide range of species.
Recommended TET2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC
Validations
- (7)
Cat. No.
ABIN7193624
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC
Validations
- (5)
Cat. No.
ABIN7261632
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (5)
Cat. No.
ABIN1513598
Quantity
100 μg
Datasheet
Datasheet
Recommended TET2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970599
Quantity
96 tests
Datasheet
Datasheet
Recommended TET2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
Cat. No.
ABIN7535260
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
Cat. No.
ABIN7535933
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
Cat. No.
ABIN7535088
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our TET2 products
: "Differences in DNA Methylation Reprogramming Underlie the Sexual Dimorphism of Behavioral Disorder Caused by Prenatal Stress in Rats." in: Frontiers in neuroscience, Vol. 14, pp. 573107, (2020) (PubMed).: "Ascorbic acid induces global epigenetic reprogramming to promote meiotic maturation and developmental competence of porcine oocytes." in: Scientific reports, Vol. 8, Issue 1, pp. 6132, (2018) (PubMed).
: "Epigenetic Reprogramming Strategies to Reverse Global Loss of 5-Hydroxymethylcytosine, a Prognostic Factor for Poor Survival in High-grade Serous Ovarian Cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 24, Issue 6, pp. 1389-1401, (2018) (PubMed).
: "Silencing HIF-1α induces TET2 expression and augments ascorbic acid induced 5-hydroxymethylation of DNA in human metastatic melanoma cells." in: Biochemical and biophysical research communications, Vol. 490, Issue 2, pp. 176-181, (2017) (PubMed).
: "Epigenetic dynamics of monocyte-to-macrophage differentiation. ..." in: Epigenetics & chromatin, Vol. 9, pp. 33, (2016) (PubMed).
: "Epigenetic silencing of TET2 and TET3 induces an EMT-like process in melanoma." in: Oncotarget, Vol. 8, Issue 1, pp. 315-328, (2016) (PubMed).
: "Reduction of global 5-hydroxymethylcytosine is a poor prognostic factor in breast cancer patients, especially for an ER/PR-negative subtype." in: Breast cancer research and treatment, Vol. 153, Issue 1, pp. 219-34, (2015) (PubMed).
: "Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma." in: PLoS ONE, Vol. 7, Issue 7, pp. e41036, (2012) (PubMed).
: "Acquired mutations in TET2 are common in myelodysplastic syndromes." in: Nature genetics, Vol. 41, Issue 7, pp. 838-42, (2009) (PubMed).
Synonyms and alternative names related to TET2
tet methylcytosine dioxygenase 2 (TET2), tet methylcytosine dioxygenase 2 (Tet2), Ayu17-449, E130014J05Rik, KIAA1546, MDS, mKIAA1546, RGD1311625Protein level used designations for TET2
- methylcytosine dioxygenase TET2
- probable methylcytosine dioxygenase TET2
- tet oncogene family member 2
- tet oncogene 2
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