TdT Products
(Deoxynucleotidyltransferase, terminal (DNTT))
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This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008].
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Featured TdT Categories
TdT Antibodies
High quality antibodies with extensive validation data.
TdT ELISA Kits
Reliable ELISA kits for a wide range of species.
TdT Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TdT Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS
Validations
- (5)
Cat. No.
ABIN5542551
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (4)
Cat. No.
ABIN5542550
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN560634
Quantity
100 μg
Datasheet
Datasheet
Recommended TdT ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966320
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1130055
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Validations
Cat. No.
ABIN1130053
Quantity
96 tests
Datasheet
Datasheet
Recommended TdT Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351877
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3073778
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN5709413
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our TdT products
: "Analyzing tumor heterogeneity and driver genes in single myeloid leukemia cells with SBCapSeq." in: Nature biotechnology, Vol. 34, Issue 9, pp. 962-72, (2016) (PubMed).: "Functional analyses of polymorphic variants of human terminal deoxynucleotidyl transferase." in: Genes and immunity, Vol. 16, Issue 6, pp. 388-98, (2015) (PubMed).
: "Bone morphogenetic protein 7 upregulates the expression of nestin and glial fibrillary acidic protein in rats with cerebral ischemia-reperfusion injury." in: Biomedical reports, Vol. 1, Issue 6, pp. 895-900, (2014) (PubMed).
: "Antitumour activity of the recombination polypeptide GST-NT21MP is mediated by inhibition of CXCR4 pathway in breast cancer." in: British journal of cancer, Vol. 110, Issue 5, pp. 1288-97, (2014) (PubMed).
: "Histopathological studies of microtubule disassembling agent-induced myocardial lesions in rats." in: Experimental and toxicologic pathology : official journal of the Gesellschaft fu?r Toxikologische Pathologie, Vol. 65, Issue 6, pp. 737-43, (2013) (PubMed).
: "Annexin A3 is associated with a poor prognosis in breast cancer and participates in the modulation of apoptosis in vitro by affecting the Bcl-2/Bax balance." in: Experimental and molecular pathology, Vol. 95, Issue 1, pp. 23-31, (2013) (PubMed).
: "Combined adenovirus-mediated artificial microRNAs targeting mfgl2, mFas, and mTNFR1 protect against fulminant hepatic failure in mice." in: PLoS ONE, Vol. 8, Issue 11, pp. e82330, (2013) (PubMed).
: "Coexistence of hyperlipidemia and acute cerebral ischemia/reperfusion induces severe liver damage in a rat model." in: World journal of gastroenterology, Vol. 18, Issue 35, pp. 4934-43, (2012) (PubMed).
Synonyms and alternative names related to TdT
DNA nucleotidylexotransferase (DNTT), deoxynucleotidyltransferase, terminal (dntt), deoxynucleotidyltransferase, terminal (Dntt), DNA nucleotidylexotransferase L homeolog (dntt.L), DNA nucleotidylexotransferase (Dntt), terminal deoxynucleotidyl transferase (tdt), BB160593, dntt, dntt-A, TdT, TDT, TdtProtein level used designations for TdT
- terminal deoxynucleotidyltransferase
- DNA nucleotidylexotransferase
- terminal deoxynucleotidyl transferase
- TDT
- terminal addition enzyme
- terminal transferase
- deoxynucleotidyltransferase, terminal
- nucleosidetriphosphate:DNA deoxynucleotidylexotransferase
- terminal deoxyribonucleotidyltransferase
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