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TDP2 Products

(tyrosyl-DNA phosphodiesterase 2 (TDP2))

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This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors. [provided by RefSeq, Jul 2008].

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Featured TDP2 Categories

TDP2 Antibodies

High quality antibodies with extensive validation data.

TDP2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TDP2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, FACS, IHC (p)
Validations
  • (4)
Cat. No. ABIN655180
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (1)
  • (2)
Cat. No. ABIN526818
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (3)
Cat. No. ABIN526819
Quantity 100 μg
Datasheet Datasheet

Recommended TDP2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6228275
Quantity 96 tests
Datasheet Datasheet

Recommended TDP2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324089
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324087
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7280202
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our TDP2 products

Cheung: "Specific functions of the Rep and Rep׳ proteins of porcine circovirus during copy-release and rolling-circle DNA replication." in: Virology, Vol. 481, pp. 43-50, (2015) (PubMed).

Thomson, Watson, Caldecott, Denneny, Depledge, Hamilton, Hopkins, Jordan, Morrow, Raoof, Waddell, Ogilvie: "Generation of assays and antibodies to facilitate the study of human 5'-tyrosyl DNA phosphodiesterase." in: Analytical biochemistry, Vol. 436, Issue 2, pp. 145-50, (2013) (PubMed).

Virgen-Slane, Rozovics, Fitzgerald, Ngo, Chou, van der Heden van Noort, Filippov, Gershon, Semler: "An RNA virus hijacks an incognito function of a DNA repair enzyme." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 36, pp. 14634-9, (2012) (PubMed).

Xu, Pan, Wang, Huang, Tian, Xue, Chen, Jia: "TTRAP is a novel PML nuclear bodies-associated protein." in: Biochemical and biophysical research communications, Vol. 375, Issue 3, pp. 395-8, (2008) (PubMed).

Synonyms and alternative names related to TDP2

tyrosyl-DNA phosphodiesterase 2 (TDP2), tyrosyl-DNA phosphodiesterase 2 S homeolog (tdp2.S), tyrosyl-DNA phosphodiesterase 2 (Tdp2), tyrosyl-DNA phosphodiesterase 2b (tdp2b), AD022, ad022, D13Ertd656e, dJ30M3.3, EAP2, eap2, EAPII, hTDP2, tdp2, TTRAP, ttrap, Ttrap, ttrapl

Protein level used designations for TDP2

  • 5'-Tyr-DNA phosphodiesterase
  • 5'-tyrosyl-DNA phosphodiesterase
  • ETS1-associated protein 2
  • ETS1-associated protein II
  • TRAF and TNF receptor associated protein
  • TRAF and TNF receptor-associated protein
  • VPg unlinkase
  • tyr-DNA phosphodiesterase 2
  • tyrosyl-RNA phosphodiesterase
  • TRAF and TNF receptor-associated protein homolog
  • Tyr-DNA phosphodiesterase 2
  • Traf and Tnf receptor associated protein
  • immune transcriptional repressor
  • traf and tnf receptor associated protein, like
  • tyrosyl-DNA phosphodiesterase 2
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