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TDGF1 Products

(Teratocarcinoma-Derived Growth Factor 1 (TDGF1))

Categories

This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010].

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Featured TDGF1 Categories

TDGF1 Antibodies

High quality antibodies with extensive validation data.

TDGF1 ELISA Kits

Reliable ELISA kits for a wide range of species.

TDGF1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TDGF1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (5)
Cat. No. ABIN3021342
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (3)
Cat. No. ABIN7007414
Quantity 60 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB, IHC, IF, ICC
Validations
  • (2)
Cat. No. ABIN6265513
Quantity 100 μL
Datasheet Datasheet

Recommended TDGF1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970586
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970587
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959889
Quantity 96 tests
Datasheet Datasheet

Recommended TDGF1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322428
Quantity 10 μg
Datasheet Datasheet
Reactivity Rat
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7198209
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7504538
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our TDGF1 products

Gudbergsson, Duroux: "An evaluation of different Cripto-1 antibodies and their variable results." in: Journal of cellular biochemistry, (2019) (PubMed).

Sun, Yan, Shi, Wan, Jiang, Fu, Li, Guo: "MicroRNA-15b suppresses the growth and invasion of glioma cells through targeted inhibition of cripto-1 expression." in: Molecular medicine reports, Vol. 13, Issue 6, pp. 4897-903, (2016) (PubMed).

Lee, Jung, Cho, Kim, Lee, Kim, Lee, Shim: "GRP78 Protein Expression as Prognostic Values in Neoadjuvant Chemoradiotherapy and Laparoscopic Surgery for Locally Advanced Rectal Cancer." in: Cancer research and treatment : official journal of Korean Cancer Association, Vol. 47, Issue 4, pp. 804-12, (2015) (PubMed).

Loying, Manhas, Sen, Bose: "Autoregulation and heterogeneity in expression of human Cripto-1." in: PLoS ONE, Vol. 10, Issue 2, pp. e0116748, (2015) (PubMed).

Sun, Shi, Li, Jiang, Fu, Guo: "Lefty inhibits glioma growth by suppressing Nodal-activated Smad and ERK1/2 pathways." in: Journal of the neurological sciences, Vol. 347, Issue 1-2, pp. 137-42, (2014) (PubMed).

Watanabe, Bianco, Strizzi, Hamada, Mancino, Bailly, Mo, Wen, Miatkowski, Gonzales, Sanicola, Seno, Salomon: "Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration." in: The Journal of biological chemistry, Vol. 282, Issue 43, pp. 31643-55, (2007) (PubMed).

Watanabe, Hamada, Bianco, Mancino, Nagaoka, Gonzales, Bailly, Strizzi, Salomon: "Requirement of glycosylphosphatidylinositol anchor of Cripto-1 for trans activity as a Nodal co-receptor." in: The Journal of biological chemistry, Vol. 282, Issue 49, pp. 35772-86, (2007) (PubMed).

Xing, Hu, Pietersz, Hosick, McKenzie: "Cripto: a novel target for antibody-based cancer immunotherapy." in: Cancer research, Vol. 64, Issue 11, pp. 4018-23, (2004) (PubMed).

Gray, Harrison, Vale: "Cripto forms a complex with activin and type II activin receptors and can block activin signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 9, pp. 5193-8, (2003) (PubMed).

Parisi, DAndrea, Lago, Adamson, Persico, Minchiotti: "Nodal-dependent Cripto signaling promotes cardiomyogenesis and redirects the neural fate of embryonic stem cells." in: The Journal of cell biology, Vol. 163, Issue 2, pp. 303-14, (2003) (PubMed).

Synonyms and alternative names related to TDGF1

teratocarcinoma-derived growth factor 1 (TDGF1), teratocarcinoma-derived growth factor 1 (Tdgf1), teratocarcinoma-derived growth factor 1 (tdgf1), teratocarcinoma-derived growth factor 1, member 3 L homeolog (tdgf1.3.L), teratocarcinoma-derived growth factor 1, member 1 (tdgf1.1), cb85, CR, CR1, cr1, cr1a, CRGF, CRIPTO, cripto, Cripto-1, cripto-3, frl-1, frl1, tdgf1, TDGF1, tdgf3, wu:fe01d04, xcr1, zgc:109829

Protein level used designations for TDGF1

  • cripto-1 growth factor
  • epidermal growth factor-like cripto protein CR1
  • TERATOCARCINOMA-DERIVED GROWTH FACTOR PRECURSOR (EPIDERMAL GROWTH FACTOR-LIKE CRIPTO PROTEIN) (CRIPTO GROWTH FACTOR)
  • cripto growth factor
  • epidermal growth factor-like Cripto protein
  • teratocarcinoma-derived growth factor
  • cryptic protein
  • one eyed pinhead
  • teratocarcinoma-derived growth factor 1
  • cripto-1a
  • fibroblast growth factor receptor ligand 1
  • teratocarcinoma-derived growth factor 3
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