TCL1A Products
(T-Cell Leukemia/lymphoma 1A (TCL1A))
Categories
Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).[supplied by OMIM, Jul 2010].
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Featured TCL1A Categories
TCL1A Antibodies
High quality antibodies with extensive validation data.
TCL1A ELISA Kits
Reliable ELISA kits for a wide range of species.
TCL1A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TCL1A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, StM
Validations
- (5)
Cat. No.
ABIN6940949
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS
Validations
- (4)
Cat. No.
ABIN5542543
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, StM
Validations
- (4)
Cat. No.
ABIN6940948
Quantity
100 μg
Datasheet
Datasheet
Recommended TCL1A ELISA Kits
Recommended TCL1A Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN935060
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322390
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322394
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our TCL1A products
: "Estrogen, SNP-Dependent Chemokine Expression and Selective Estrogen Receptor Modulator Regulation." in: Molecular endocrinology (Baltimore, Md.), Vol. 30, Issue 3, pp. 382-98, (2016) (PubMed).: "CD34 affinity pheresis attenuates a surge among circulating progenitor cells following vascular injury." in: Journal of vascular surgery, Vol. 59, Issue 6, pp. 1686-94, (2014) (PubMed).
: "Integrated high-power electro-optic lens and large-angle deflector." in: Applied optics, Vol. 40, Issue 31, pp. 5638-42, (2008) (PubMed).
: "Characteristic expression patterns of TCL1, CD38, and CD44 identify aggressive lymphomas harboring a MYC translocation." in: The American journal of surgical pathology, Vol. 32, Issue 1, pp. 113-22, (2007) (PubMed).
: "Expression of TCL1 and CD27 in primary cutaneous B-cell lymphomas." in: Histopathology, Vol. 49, Issue 4, pp. 343-8, (2006) (PubMed).
: "Dysregulated TCL1 requires the germinal center and genome instability for mature B-cell transformation." in: Blood, Vol. 108, Issue 6, pp. 1991-8, (2006) (PubMed).
: "Expression of TCL1 in hematologic disorders." in: Pathobiology : journal of immunopathology, molecular and cellular biology, Vol. 69, Issue 2, pp. 59-66, (2001) (PubMed).
: "The role of TCL1 in human T-cell leukemia." in: Oncogene, Vol. 20, Issue 40, pp. 5638-43, (2001) (PubMed).
: "Activation of the TCL1 protein in B cell lymphomas." in: Pathology international, Vol. 50, Issue 3, pp. 191-9, (2000) (PubMed).
: "Regulation of TCL1 expression in B- and T-cell lymphomas and reactive lymphoid tissues." in: Cancer research, Vol. 60, Issue 8, pp. 2095-100, (2000) (PubMed).
Synonyms and alternative names related to TCL1A
T-cell leukemia/lymphoma 1A (TCL1A), T cell lymphoma breakpoint 1 (Tcl1), T-cell leukemia/lymphoma 1A (Tcl1a), TCL1, Tcl1, TCL1A, Tcl1aProtein level used designations for TCL1A
- T-cell leukemia/lymphoma 1A
- T-cell lymphoma-1
- T-cell leukemia/lymphoma protein 1A
- T-cell lymphoma breakpoint 1
- TCL-1
- oncogene TCL-1
- oncogene TCL1
- protein p14 TCL1
- T-cell leukemia/lymphoma protein 1A (P14 TCL1 protein) (TCL1 oncogene) (TCL-1 protein)
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