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TCF7 Products

(Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))

Categories

The protein encoded by this gene is a transcriptional activator that plays an important role in lymphocyte differentiation. This gene is expressed predominantly in T-cells. The encoded protein can bind an enhancer element and activate the CD3E gene, and it also may repress the CTNNB1 and TCF7L2 genes through a feedback mechanism. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].

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Featured TCF7 Categories

TCF7 Antibodies

High quality antibodies with extensive validation data.

TCF7 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TCF7 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, CUT&RUN
Validations
  • (1)
  • (2)
  • (1)
Cat. No. ABIN5620945
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IHC, IF
Validations
  • (5)
Cat. No. ABIN7075952
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IF
Validations
  • (5)
Cat. No. ABIN563114
Quantity 100 μg
Datasheet Datasheet

Recommended TCF7 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative DNA-Binding ELISA
Validations
Cat. No. ABIN5648577
Quantity 96 tests
Datasheet Datasheet

Recommended TCF7 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322372
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322371
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3073872
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TCF7 products

Johnson, Drugan, Miller, Evans: "38" in: , Vol. 1363, Issue Nucleic acids research, pp. 28-39, (1991)

Zambanini, Nordin, Jonasson, Pagella, Cantù: "A new cut&run low volume-urea (LoV-U) protocol optimized for transcriptional co-factors uncovers Wnt/b-catenin tissue-specific genomic targets." in: Development (Cambridge, England), (2022) (PubMed).

Campbell, Ussher, Mulvihill, Kolic, Baggio, Cao, Liu, Lamont, Morii, Streutker, Tamarina, Philipson, Wrana, MacDonald, Drucker: "TCF1 links GIPR signaling to the control of beta cell function and survival." in: Nature medicine, Vol. 22, Issue 1, pp. 84-90, (2016) (PubMed).

Kaur, Vig, Srivastava, Mishra, Singh, Srivastava, Datta: "Elevated hepatic miR-22-3p expression impairs gluconeogenesis by silencing the Wnt-responsive transcription factor, Tcf7." in: Diabetes, (2015) (PubMed).

Smit, Baas, Kuipers, Korswagen, van de Wetering, Clevers: "Wnt activates the Tak1/Nemo-like kinase pathway." in: The Journal of biological chemistry, Vol. 279, Issue 17, pp. 17232-40, (2004) (PubMed).

Noble, White, Lazzeroni, Valdes, Mirel, Reynolds, Grupe, Aud, Peltz, Erlich: "A polymorphism in the TCF7 gene, C883A, is associated with type 1 diabetes." in: Diabetes, Vol. 52, Issue 6, pp. 1579-82, (2003) (PubMed).

Ioannidis, Kunz, Tanamachi, Scarpellino, Held: "Initiation and limitation of Ly-49A NK cell receptor acquisition by T cell factor-1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 2, pp. 769-75, (2003) (PubMed).

Synonyms and alternative names related to TCF7

transcription factor 7 (TCF7), transcription factor 7, T cell specific (Tcf7), transcription factor 7 (Tcf7), transcription factor 7 (tcf7), transcription factor 7 S homeolog (tcf7.S), AI465550, TCF-1, tcf-1, Tcf1, tcf1, tcf7, Xtcf-1, Xtcf1

Protein level used designations for TCF7

  • T-cell-specific transcription factor 1
  • transcription factor 7
  • T cell factor-1
  • T-cell factor 1
  • TCF-7
  • transcription factor 7, T-cell specific
  • transcription factor 7 (T-cell specific, HMG-box)
  • T-cell factor 7
  • T cell-specific transcription factor 1
  • transcription factor 7 (T-cell specific, HMG-box) S homeolog
  • transcription factor 7 S homeolog
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