TCEB1 Products
(Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1))
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This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified. [provided by RefSeq, Mar 2011].
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Featured TCEB1 Categories
TCEB1 Antibodies
High quality antibodies with extensive validation data.
TCEB1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TCEB1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (3)
Cat. No.
ABIN6148930
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ICC, IP
Validations
- (2)
Cat. No.
ABIN7445219
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC
Validations
- (2)
Cat. No.
ABIN7128027
Quantity
100 μL
Datasheet
Datasheet
Recommended TCEB1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6228298
Quantity
96 tests
Datasheet
Datasheet
Recommended TCEB1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322346
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7419931
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3079547
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our TCEB1 products
: "An ID2-dependent mechanism for VHL inactivation in cancer." in: Nature, Vol. 529, Issue 7585, pp. 172-7, (2016) (PubMed).: "MCM proteins are negative regulators of hypoxia-inducible factor 1." in: Molecular cell, Vol. 42, Issue 5, pp. 700-12, (2011) (PubMed).
: "COMMD1 (copper metabolism MURR1 domain-containing protein 1) regulates Cullin RING ligases by preventing CAND1 (Cullin-associated Nedd8-dissociated protein 1) binding." in: The Journal of biological chemistry, Vol. 286, Issue 37, pp. 32355-65, (2011) (PubMed).
: "GCN5 is a required cofactor for a ubiquitin ligase that targets NF-kappaB/RelA." in: Genes & development, Vol. 23, Issue 7, pp. 849-61, (2009) (PubMed).
: "COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase." in: The EMBO journal, Vol. 26, Issue 2, pp. 436-47, (2007) (PubMed).
: "RNA polymerase II transcription factor SIII. I. Identification, purification, and properties." in: The Journal of biological chemistry, Vol. 268, Issue 34, pp. 25587-93, (1994) (PubMed).
Synonyms and alternative names related to TCEB1
elongin C (Eloc), elongin C L homeolog (eloc.L), elongin C (ELOC), transcription elongation factor B (SIII), polypeptide 1b (tceb1b), 2610043E24Rik, 2610301I15Rik, AA407206, AI987979, AW049146, eloC, fb09f09, SIII, TCEB1, wu:fb09f09, zgc:92635, zgc:111990Protein level used designations for TCEB1
- RNA polymerase II transcription factor SIII subunit C
- SIII p15
- eloC
- elongin 15 kDa subunit
- elongin C
- elongin-C
- stromal membrane-associated protein SMAP1B homolog
- transcription elongation factor B polypeptide 1
- elongation factor SIII p15 subunit
- Elongin C
- transcription elongation factor B (SIII), polypeptide 1
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