Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

TCEB1 Products

(Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1))

Categories

This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified. [provided by RefSeq, Mar 2011].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured TCEB1 Categories

TCEB1 Antibodies

High quality antibodies with extensive validation data.

TCEB1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TCEB1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN6148930
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC, IP
Validations
  • (2)
Cat. No. ABIN7445219
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IHC
Validations
  • (2)
Cat. No. ABIN7128027
Quantity 100 μL
Datasheet Datasheet

Recommended TCEB1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6228298
Quantity 96 tests
Datasheet Datasheet

Recommended TCEB1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322346
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7419931
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3079547
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TCEB1 products

Lee, Frattini, Bansal, Castano, Sherman, Hutchinson, Bruce, Califano, Liu, Cardozo, Iavarone, Lasorella: "An ID2-dependent mechanism for VHL inactivation in cancer." in: Nature, Vol. 529, Issue 7585, pp. 172-7, (2016) (PubMed).

Hubbi, Luo, Baek, Semenza: "MCM proteins are negative regulators of hypoxia-inducible factor 1." in: Molecular cell, Vol. 42, Issue 5, pp. 700-12, (2011) (PubMed).

Mao, Gluck, Chen, Starokadomskyy, Li, Maine, Burstein: "COMMD1 (copper metabolism MURR1 domain-containing protein 1) regulates Cullin RING ligases by preventing CAND1 (Cullin-associated Nedd8-dissociated protein 1) binding." in: The Journal of biological chemistry, Vol. 286, Issue 37, pp. 32355-65, (2011) (PubMed).

Mao, Gluck, Li, Maine, Li, Zaidi, Repaka, Mayo, Burstein: "GCN5 is a required cofactor for a ubiquitin ligase that targets NF-kappaB/RelA." in: Genes & development, Vol. 23, Issue 7, pp. 849-61, (2009) (PubMed).

Maine, Mao, Komarck, Burstein: "COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase." in: The EMBO journal, Vol. 26, Issue 2, pp. 436-47, (2007) (PubMed).

Bradsher, Jackson, Conaway, Conaway: "RNA polymerase II transcription factor SIII. I. Identification, purification, and properties." in: The Journal of biological chemistry, Vol. 268, Issue 34, pp. 25587-93, (1994) (PubMed).

Synonyms and alternative names related to TCEB1

elongin C (Eloc), elongin C L homeolog (eloc.L), elongin C (ELOC), transcription elongation factor B (SIII), polypeptide 1b (tceb1b), 2610043E24Rik, 2610301I15Rik, AA407206, AI987979, AW049146, eloC, fb09f09, SIII, TCEB1, wu:fb09f09, zgc:92635, zgc:111990

Protein level used designations for TCEB1

  • RNA polymerase II transcription factor SIII subunit C
  • SIII p15
  • eloC
  • elongin 15 kDa subunit
  • elongin C
  • elongin-C
  • stromal membrane-associated protein SMAP1B homolog
  • transcription elongation factor B polypeptide 1
  • elongation factor SIII p15 subunit
  • Elongin C
  • transcription elongation factor B (SIII), polypeptide 1
You are here:
Support