TCAP Products
(Titin-Cap (Telethonin) (TCAP))
Categories
Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. [provided by RefSeq, Jul 2008].
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Featured TCAP Categories
TCAP Antibodies
High quality antibodies with extensive validation data.
TCAP Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TCAP Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN522010
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA
Validations
- (2)
Cat. No.
ABIN7171700
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC, ELISA
Validations
- (2)
Cat. No.
ABIN6259225
Quantity
100 μL
Datasheet
Datasheet
Recommended TCAP Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322319
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322316
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3074021
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our TCAP products
: "A pilot study of muscle plasma protein changes after exercise." in: Muscle & nerve, Vol. 49, Issue 2, pp. 261-6, (2014) (PubMed).: "Early and selective disappearance of telethonin protein from the sarcomere in neurogenic atrophy." in: Journal of muscle research and cell motility, Vol. 22, Issue 3, pp. 259-64, (2001) (PubMed).
: "Limb-girdle muscular dystrophy type 2G is caused by mutations in the gene encoding the sarcomeric protein telethonin." in: Nature genetics, Vol. 24, Issue 2, pp. 163-6, (2000) (PubMed).
: "The novel sarcomeric protein telethonin exhibits developmental and functional regulation." in: Biochemical and biophysical research communications, Vol. 257, Issue 3, pp. 699-703, (1999) (PubMed).
: "Telethonin, a novel sarcomeric protein of heart and skeletal muscle." in: FEBS letters, Vol. 415, Issue 2, pp. 163-8, (1997) (PubMed).
Synonyms and alternative names related to TCAP
titin-cap (TCAP), titin-cap (telethonin) (tcap), titin-cap (tcap), titin-cap S homeolog (tcap.S), titin-cap (Tcap), AI503981, AJ223855, CMD1N, LGMD2G, T-cap, TCAP, TELE, telethoninProtein level used designations for TCAP
- titin-cap (telethonin)
- 19 kDa sarcomeric protein
- limb girdle muscular dystrophy 2G (autosomal recessive)
- telethonin
- titin cap protein
- titin-cap protein
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