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TCAP Products

(Titin-Cap (Telethonin) (TCAP))

Categories

Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. [provided by RefSeq, Jul 2008].

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Featured TCAP Categories

TCAP Antibodies

High quality antibodies with extensive validation data.

TCAP Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TCAP Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN522010
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7171700
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN6259225
Quantity 100 μL
Datasheet Datasheet

Recommended TCAP Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322319
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322316
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3074021
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TCAP products

Dahlqvist, Voss, Lauridsen, Krag, Vissing: "A pilot study of muscle plasma protein changes after exercise." in: Muscle & nerve, Vol. 49, Issue 2, pp. 261-6, (2014) (PubMed).

Schröder, Reimann, Iakovenko, Mues, Bönnemann, Matten, Gautel: "Early and selective disappearance of telethonin protein from the sarcomere in neurogenic atrophy." in: Journal of muscle research and cell motility, Vol. 22, Issue 3, pp. 259-64, (2001) (PubMed).

Moreira, Wiltshire, Faulkner, Nilforoushan, Vainzof, Suzuki, Valle, Reeves, Zatz, Passos-Bueno, Jenne: "Limb-girdle muscular dystrophy type 2G is caused by mutations in the gene encoding the sarcomeric protein telethonin." in: Nature genetics, Vol. 24, Issue 2, pp. 163-6, (2000) (PubMed).

Mason, Bayol, Loughna: "The novel sarcomeric protein telethonin exhibits developmental and functional regulation." in: Biochemical and biophysical research communications, Vol. 257, Issue 3, pp. 699-703, (1999) (PubMed).

Valle, Faulkner, De Antoni, Pacchioni, Pallavicini, Pandolfo, Tiso, Toppo, Trevisan, Lanfranchi: "Telethonin, a novel sarcomeric protein of heart and skeletal muscle." in: FEBS letters, Vol. 415, Issue 2, pp. 163-8, (1997) (PubMed).

Synonyms and alternative names related to TCAP

titin-cap (TCAP), titin-cap (telethonin) (tcap), titin-cap (tcap), titin-cap S homeolog (tcap.S), titin-cap (Tcap), AI503981, AJ223855, CMD1N, LGMD2G, T-cap, TCAP, TELE, telethonin

Protein level used designations for TCAP

  • titin-cap (telethonin)
  • 19 kDa sarcomeric protein
  • limb girdle muscular dystrophy 2G (autosomal recessive)
  • telethonin
  • titin cap protein
  • titin-cap protein
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