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TBCC Products

(Tubulin Folding Cofactor C (TBCC))

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Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex\; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. [provided by RefSeq, Jul 2008].

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Featured TBCC Categories

TBCC Antibodies

High quality antibodies with extensive validation data.

TBCC Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TBCC Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, ICC
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Cat. No. ABIN5542597
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Rat
Application WB, IHC, IF, IHC (p)
Validations
  • (9)
Cat. No. ABIN1501323
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (3)
  • (3)
Cat. No. ABIN520721
Quantity 100 μg
Datasheet Datasheet

Recommended TBCC ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6227432
Quantity 96 tests
Datasheet Datasheet

Recommended TBCC Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322240
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN6387011
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2132082
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our TBCC products

Hage-Sleiman, Herveau, Matera, Laurier, Dumontet: "Silencing of tubulin binding cofactor C modifies microtubule dynamics and cell cycle distribution and enhances sensitivity to gemcitabine in breast cancer cells." in: Molecular cancer therapeutics, Vol. 10, Issue 2, pp. 303-12, (2011) (PubMed).

Garcia-Mayoral, Castaño, Fanarraga, Zabala, Rico, Bruix: "The solution structure of the N-terminal domain of human tubulin binding cofactor C reveals a platform for tubulin interaction." in: PLoS ONE, Vol. 6, Issue 10, pp. e25912, (2011) (PubMed).

Hage-Sleiman, Herveau, Matera, Laurier, Dumontet: "Tubulin binding cofactor C (TBCC) suppresses tumor growth and enhances chemosensitivity in human breast cancer cells." in: BMC cancer, Vol. 10, pp. 135, (2010) (PubMed).

Synonyms and alternative names related to TBCC

tubulin folding cofactor C (TBCC), tubulin folding cofactor C (Tbcc), tubulin-specific chaperone C (Tbcc), 2810055C19Rik, CFC

Protein level used designations for TBCC

  • tubulin-folding cofactor C
  • tubulin-specific chaperone C
  • CFC
  • beta-tubulin cofactor C
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