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TBC1D4 Products

(TBC1 Domain Family, Member 4 (TBC1D4))

Categories

May act as a GTPase-activating protein for RAB2A, RAB8A, RAB10 and RAB14. Isoform 2 promotes insulin-induced glucose transporter SLC2A4/GLUT4 translocation at the plasma membrane, thus increasing glucose uptake.

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Featured TBC1D4 Categories

TBC1D4 Antibodies

High quality antibodies with extensive validation data.

TBC1D4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TBC1D4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB, IHC, FACS, ICC, Neut
Validations
  • (4)
Cat. No. ABIN5684096
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7171654
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (3)
Cat. No. ABIN652462
Quantity 400 μL
Datasheet Datasheet

Recommended TBC1D4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3095800
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3136316
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2733279
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our TBC1D4 products

Stöckli, Davey, Hohnen-Behrens, Xu, James, Ramm: "Regulation of glucose transporter 4 translocation by the Rab guanosine triphosphatase-activating protein AS160/TBC1D4: role of phosphorylation and membrane association." in: Molecular endocrinology (Baltimore, Md.), Vol. 22, Issue 12, pp. 2703-15, (2008) (PubMed).

Karlsson, Zierath, Kane, Krook, Lienhard, Wallberg-Henriksson: "Insulin-stimulated phosphorylation of the Akt substrate AS160 is impaired in skeletal muscle of type 2 diabetic subjects." in: Diabetes, Vol. 54, Issue 6, pp. 1692-7, (2005) (PubMed).

Synonyms and alternative names related to TBC1D4

TBC1 domain family member 4 (TBC1D4), TBC1 domain family, member 4 (Tbc1d4), 5930406J04Rik, A930035N22, AS160, As160, AV295684, RGD1561609

Protein level used designations for TBC1D4

  • Acrg embryonic lethality minimal region ortholog
  • TBC (Tre-2, BUB2, CDC16) domain-containing protein
  • TBC1 domain family member 4
  • akt substrate of 160 kDa
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