TARBP2 Products
(TAR (HIV-1) RNA Binding Protein 2 (TARBP2))
Categories
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene. [provided by RefSeq, Jul 2008].
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Featured TARBP2 Categories
TARBP2 Antibodies
High quality antibodies with extensive validation data.
TARBP2 ELISA Kits
Reliable ELISA kits for a wide range of species.
TARBP2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TARBP2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (6)
Cat. No.
ABIN7270729
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IP
Validations
- (4)
Cat. No.
ABIN520702
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Chicken, Horse, Human, Monkey, Mouse, Rat
Application
WB, IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN207742
Quantity
100 μg
Datasheet
Datasheet
Recommended TARBP2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970562
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6210883
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1156063
Quantity
96 tests
Datasheet
Datasheet
Recommended TARBP2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322155
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322154
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2132068
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our TARBP2 products
: "Metastasis-suppressor transcript destabilization through TARBP2 binding of mRNA hairpins." in: Nature, Vol. 513, Issue 7517, pp. 256-60, (2014) (PubMed).: "A TARBP2-dependent miRNA expression profile underlies cancer stem cell properties and provides candidate therapeutic reagents in Ewing sarcoma." in: Cancer cell, Vol. 21, Issue 6, pp. 807-21, (2012) (PubMed).
: "Viral RNAi suppressor reversibly binds siRNA to outcompete Dicer and RISC via multiple turnover." in: Journal of molecular biology, Vol. 408, Issue 2, pp. 262-76, (2011) (PubMed).
: "A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment." in: Nature cell biology, Vol. 10, Issue 8, pp. 987-93, (2008) (PubMed).
: "Small interfering RNAs against the TAR RNA binding protein, TRBP, a Dicer cofactor, inhibit human immunodeficiency virus type 1 long terminal repeat expression and viral production." in: Journal of virology, Vol. 81, Issue 10, pp. 5121-31, (2007) (PubMed).
: "TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing." in: EMBO reports, Vol. 6, Issue 10, pp. 961-7, (2005) (PubMed).
: "Merlin, a tumor suppressor, interacts with transactivation-responsive RNA-binding protein and inhibits its oncogenic activity." in: The Journal of biological chemistry, Vol. 279, Issue 29, pp. 30265-73, (2004) (PubMed).
: "Identification of a group of cellular cofactors that stimulate the binding of RNA polymerase II and TRP-185 to human immunodeficiency virus 1 TAR RNA." in: The Journal of biological chemistry, Vol. 271, Issue 8, pp. 4201-8, (1996) (PubMed).
: "The cellular factor TRP-185 regulates RNA polymerase II binding to HIV-1 TAR RNA." in: The EMBO journal, Vol. 14, Issue 23, pp. 5995-6009, (1996) (PubMed).
: "Characterization of a human TAR RNA-binding protein that activates the HIV-1 LTR." in: Science (New York, N.Y.), Vol. 251, Issue 5001, pp. 1597-600, (1991) (PubMed).
Synonyms and alternative names related to TARBP2
TAR (HIV-1) RNA binding protein 2 (tarbp2), TARBP2, RISC loading complex RNA binding subunit (TARBP2), TAR (HIV-1) RNA binding protein 2 L homeolog (tarbp2.L), TARBP2, RISC loading complex RNA binding subunit (Tarbp2), TAR (HIV) RNA binding protein 2 (tarbp2), fj51e12, LOQS, MGC97783, Prbp, TARBP2, trbp, TRBP, trbp1, TRBP1, trbp2, TRBP2, wu:fj51e12, zgc:63778Protein level used designations for TARBP2
- TAR (HIV-1) RNA binding protein 2
- RISC-loading complex subunit tarbp2
- RISC-loading complex subunit TARBP2
- TAR (HIV) RNA binding protein 2
- TAR (HIV) RNA-binding protein 2
- TAR (HIV) RNA-binding protein TRBP1
- TAR RNA binding protein 2
- TAR RNA-binding protein 2
- trans-activation responsive RNA-binding protein
- trans-activation-responsive RNA-binding protein
- PRM-1 RNA-binding protein
- protamine-1 RNA-binding protein
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