TAP2 Products
(Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2))
Categories
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces two products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. [provided by RefSeq, Jul 2008].
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Featured TAP2 Categories
TAP2 Antibodies
High quality antibodies with extensive validation data.
TAP2 ELISA Kits
Reliable ELISA kits for a wide range of species.
TAP2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TAP2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (7)
Cat. No.
ABIN3022237
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IF (p), IF (cc), FACS, IHC (fro), IHC (p)
Validations
- (3)
Cat. No.
ABIN680123
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS
Validations
- (2)
Cat. No.
ABIN6243497
Quantity
200 μL
Datasheet
Datasheet
Recommended TAP2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1122075
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1122077
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1122076
Quantity
96 tests
Datasheet
Datasheet
Recommended TAP2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322144
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7419364
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7419367
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our TAP2 products
: "Molecular profiling and clinical outcome of high-grade serous ovarian cancer presenting with low- versus high-volume ascites." in: BioMed research international, Vol. 2014, pp. 367103, (2014) (PubMed).: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).
: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).
: "Genotyping TAP2 variants in North American Caucasians, Brazilians, and Africans." in: Genes and immunity, Vol. 2, Issue 1, pp. 32-40, (2001) (PubMed).
Synonyms and alternative names related to TAP2
transporter 2, ATP binding cassette subfamily B member (TAP2), transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) (Tap2), transporter 2, ATP binding cassette subfamily B member (Tap2), ABC18, ABCB3, Abcb3, AI462429, APT2, Cim, D6S217E, Ham-2, Ham2, jas, MTP2, PSF-2, PSF2, RING11, Tap-2, Y1Protein level used designations for TAP2
- ABC transporter, MHC 2
- ATP-binding cassette, sub-family B (MDR/TAP), member 3
- antigen peptide transporter 2
- peptide supply factor 2
- peptide transporter PSF2
- peptide transporter involved in antigen processing 2
- really interesting new gene 11 protein
- transporter 2, ABC (ATP binding cassette)
- ATP dependent transport protein family member
- ATP-binding cassette sub-family B member 3
- histocompatibility antigen modifier 2
- APT2
- Transporter 2 ABC (ATP binding cassette)
- ABC-transporter
- transporter 2, ABC(ATP binding cassette)
- transporter 2, ATP-binding cassette, sub-family B
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