TANK Products
(TRAF Family Member-Associated NFKB Activator (TANK))
Categories
The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010].
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Featured TANK Categories
TANK Antibodies
High quality antibodies with extensive validation data.
TANK ELISA Kits
Reliable ELISA kits for a wide range of species.
TANK Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TANK Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ICC, IP
Validations
- (3)
Cat. No.
ABIN7443464
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7172328
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (3)
Cat. No.
ABIN652041
Quantity
400 μL
Datasheet
Datasheet
Recommended TANK ELISA Kits
Recommended TANK Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN935032
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322131
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125424
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our TANK products
: "Seneca Valley Virus Suppresses Host Type I Interferon Production by Targeting Adaptor Proteins MAVS, TRIF, and TANK for Cleavage." in: Journal of virology, Vol. 91, Issue 16, (2017) (PubMed).: "STING Specifies IRF3 Phosphorylation by TBK1 in the Cytosolic DNA Signaling Pathway." in: Science signaling, Vol. 5, Issue 214, pp. ra20, (2012) (PubMed).
: "Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK." in: The Journal of biological chemistry, Vol. 282, Issue 16, pp. 11817-26, (2007) (PubMed).
: "Association of the adaptor TANK with the I kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinases." in: The Journal of biological chemistry, Vol. 277, Issue 40, pp. 37029-36, (2002) (PubMed).
: "NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase." in: The EMBO journal, Vol. 18, Issue 23, pp. 6694-704, (2000) (PubMed).
Synonyms and alternative names related to TANK
TRAF family member associated NFKB activator (TANK), TRAF family member-associated Nf-kappa B activator (Tank), TRAF family member-associated NFKB activator (Tank), TRAF family member associated NFKB activator (Tank), TRAF family member-associated NFKB activator (tank), TRAF family member associated NFKB activator L homeolog (tank.L), C86182, E430026L09Rik, I-TRAF, i-traf, ITRAF, tank, TRAF2, traf2, zgc:153048Protein level used designations for TANK
- TRAF family member-associated NF-kappa-B activator
- TRAF-interacting protein
- TRAF family member-associated NFKB activator
- TRAF family member-associated NF-kappa-B activator-like
- TRAF family member-associated Nf-kappa B activator
- TRAF interacting protein TANK
- LOW QUALITY PROTEIN: TRAF family member-associated NF-kappa-B activator
- TRAF family member-associated NF-kappaB activator
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