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TAF15 Products

(TAF15 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 68kDa (TAF15))

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This gene encodes a member of the TET family of RNA-binding proteins. The encoded protein plays a role in RNA polymerase II gene transcription as a component of a distinct subset of multi-subunit transcription initiation factor TFIID complexes. Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012].

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Featured TAF15 Categories

TAF15 Antibodies

High quality antibodies with extensive validation data.

TAF15 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TAF15 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat, Saccharomyces cerevisiae
Application WB, IHC
Validations
  • (2)
  • (5)
Cat. No. ABIN2779283
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (4)
Cat. No. ABIN6259209
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF, IHC (p), ICC
Validations
  • (4)
Cat. No. ABIN2855557
Quantity 100 μL
Datasheet Datasheet

Recommended TAF15 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6232575
Quantity 96 tests
Datasheet Datasheet

Recommended TAF15 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125313
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1989824
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2132061
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our TAF15 products

Chi, OConnell, Yamazaki, Gangopadhyay, Gygi, Reed: "Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins." in: Scientific reports, Vol. 8, Issue 1, pp. 8755, (2018) (PubMed).

Chi, OConnell, Iocolano, Coady, Yu, Gangopadhyay, Gygi, Reed: "The neurodegenerative diseases ALS and SMA are linked at the molecular level via the ASC-1 complex." in: Nucleic acids research, Vol. 46, Issue 22, pp. 11939-11951, (2018) (PubMed).

Davidson, Robinson, Hu, Mishra, Baborie, Jaros, Perry, Cairns, Richardson, Gerhard, Neary, Snowden, Bigio, Mann: "Nuclear carrier and RNA-binding proteins in frontotemporal lobar degeneration associated with fused in sarcoma (FUS) pathological changes." in: Neuropathology and applied neurobiology, Vol. 39, Issue 2, pp. 157-65, (2015) (PubMed).

Perez, Martínez, Cosme-Cruz, Perez-Crespo, Tang: "A short cis-acting motif in the M112-113 promoter region is essential for IE3 to activate M112-113 gene expression and is important for murine cytomegalovirus replication." in: Journal of virology, Vol. 87, Issue 5, pp. 2639-47, (2013) (PubMed).

Neumann, Bentmann, Dormann, Jawaid, DeJesus-Hernandez, Ansorge, Roeber, Kretzschmar, Munoz, Kusaka, Yokota, Ang, Bilbao, Rademakers, Haass, Mackenzie: "FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations." in: Brain : a journal of neurology, Vol. 134, Issue Pt 9, pp. 2595-609, (2011) (PubMed).

Schatz, Brändlein, Rückl, Hensel, Vollmers: "Diagnostic and therapeutic potential of a human antibody cloned from a cancer patient that binds to a tumor-specific variant of transcription factor TAF15." in: Cancer research, Vol. 70, Issue 1, pp. 398-408, (2010) (PubMed).

Lee, Kim, Pelletier, Kim: "Stimulation of hTAFII68 (NTD)-mediated transactivation by v-Src." in: FEBS letters, Vol. 564, Issue 1-2, pp. 188-98, (2004) (PubMed).

Synonyms and alternative names related to TAF15

TATA-box binding protein associated factor 15 (Taf15), TATA-box binding protein associated factor 15 (TAF15), 68kDa, 2610111C21Rik, Npl3, RBP56, Taf2n, TAF2N, TAFII68

Protein level used designations for TAF15

  • TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68 kDa
  • TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA binding protein 56)
  • TATA-binding protein-associated factor 2N
  • RBP56/CSMF fusion
  • TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA-binding protein 56)
  • TATA box-binding protein-associated factor 2N (RNA-binding protein 56)
  • TBP-associated factor 15
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