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TACR1 Products

(Tachykinin Receptor 1 (TACR1))
This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P. [provided by RefSeq, Sep 2008].

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Featured TACR1 Categories

TACR1 Antibodies

High quality antibodies with extensive validation data.

TACR1 ELISA Kits

Reliable ELISA kits for a wide range of species.

TACR1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TACR1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Rat
Application WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p)
Validations
  • (1)
  • (5)
Cat. No. ABIN724385
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF
Validations
  • (3)
Cat. No. ABIN190795
Quantity 100 μg
Datasheet Datasheet
Reactivity Guinea Pig, Hamster, Horse, Human, Monkey, Rabbit, Rat
Application IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN1049098
Quantity 50 μg
Datasheet Datasheet

Recommended TACR1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970545
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970544
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970543
Quantity 96 tests
Datasheet Datasheet

Recommended TACR1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322047
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322049
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322046
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our TACR1 products

Li, Wu, Yang, Zhang, He, Xu, Zhang, Tao, Luo: "Tachykinin NK1 receptor antagonist L-733,060 and substance P deletion exert neuroprotection through inhibiting oxidative stress and cell death after traumatic brain injury in mice." in: The international journal of biochemistry & cell biology, Vol. 107, pp. 154-165, (2019) (PubMed).

Li, Luo, Ning, Xiong, Wu: "Neurokinin-1 receptor antagonism improves postoperative neurocognitive disorder in mice." in: Neuroscience letters, Vol. 687, pp. 189-195, (2019) (PubMed).

Lönndahl, Rasul, Lonne-Rahm, Holst, Johansson, El-Nour, Radu Djurfeldt, Nordlind: "Tachykinin upregulation in atopic dermatitis." in: Immunopharmacology and immunotoxicology, Vol. 41, Issue 1, pp. 117-122, (2019) (PubMed).

Li, Guo, Sun, Li, Ma, Zhang, Guan, Li, Wang: "Botulinum toxin type A and gabapentin attenuate postoperative pain and NK1 receptor internalization in rats." in: Neurochemistry international, Vol. 116, pp. 52-62, (2018) (PubMed).

Wang, Tawfik, Corder, Low, François, Basbaum, Scherrer: "Functional Divergence of Delta and Mu Opioid Receptor Organization in CNS Pain Circuits." in: Neuron, Vol. 98, Issue 1, pp. 90-108.e5, (2018) (PubMed).

Bubak, Como, Blackmon, Frietze, Mescher, Jones, Cohrs, Paucek, Baird, Nagel: "Varicella Zoster Virus Induces Nuclear Translocation of the Neurokinin-1 Receptor, Promoting Lamellipodia Formation and Viral Spread in Spinal Astrocytes." in: The Journal of infectious diseases, Vol. 218, Issue 8, pp. 1324-1335, (2018) (PubMed).

Zhang, Gao, Liu, Ji, Sha: "Effects of Neuropeptide Substance P on Proliferation and β-Cell Differentiation of Adult Pancreatic Ductal Cells." in: Frontiers in neuroscience, Vol. 12, pp. 806, (2018) (PubMed).

Zhang, Zheng, Xie, Chai, Wang, Zhang, He: "Up-regulated expression of substance P in CD8(+) T cells and NK1R on monocytes of atopic dermatitis." in: Journal of translational medicine, Vol. 15, Issue 1, pp. 93, (2017) (PubMed).

Taracanova, Alevizos, Karagkouni, Weng, Norwitz, Conti, Leeman, Theoharides: "SP and IL-33 together markedly enhance TNF synthesis and secretion from human mast cells mediated by the interaction of their receptors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 20, pp. E4002-E4009, (2017) (PubMed).

Morinaga, Nakamuta, Yamamoto: "Hypoxia-induced increases in serotonin-immunoreactive nerve fibers in the medulla oblongata of the rat." in: Acta histochemica, Vol. 118, Issue 8, pp. 806-817, (2016) (PubMed).

Synonyms and alternative names related to TACR1

tachykinin receptor 1 (TACR1), tachykinin receptor 1 (Tacr1), ASPR, NK1R, Nk1r, nk1R, NKIR, SPR, Spr, TAC1R, Tac1r, Tacr1

Protein level used designations for TACR1

  • NK-1 receptor
  • NK-1R
  • substance-P receptor
  • tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor)
  • Nk1 receptor
  • neurokinin receptor 1
  • substance P receptor
  • SPR
  • neurokinin 1 receptor
  • substance p receptor
  • neurokinin receptor subtype NK1
  • tachikinin receptor 1
  • tachykinin receptor 1
  • neurokinin-1 receptor
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