TAB2 Products
(TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2))
Categories
The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. [provided by RefSeq, Jul 2008].
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Featured TAB2 Categories
TAB2 Antibodies
High quality antibodies with extensive validation data.
TAB2 ELISA Kits
Reliable ELISA kits for a wide range of species.
Recommended TAB2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB, IHC
Validations
- (1)
- (4)
Cat. No.
ABIN2779619
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS
Validations
- (3)
- (2)
Cat. No.
ABIN969430
Quantity
100 μL
Datasheet
Datasheet
Application
WB, IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN6735781
Quantity
100 μL
Datasheet
Datasheet
Recommended TAB2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970604
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6227571
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6227570
Quantity
96 tests
Datasheet
Datasheet
Recommended TAB2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125346
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3073632
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3136942
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our TAB2 products
: "Enterovirus 71 3C inhibits cytokine expression through cleavage of the TAK1/TAB1/TAB2/TAB3 complex." in: Journal of virology, Vol. 88, Issue 17, pp. 9830-41, (2014) (PubMed).: "Haploinsufficiency of TAB2 causes congenital heart defects in humans." in: American journal of human genetics, Vol. 86, Issue 6, pp. 839-49, (2010) (PubMed).
: "Regulation and function of IKK and IKK-related kinases." in: Science's STKE : signal transduction knowledge environment, Vol. 2006, Issue 357, pp. re13, (2006) (PubMed).
: "Contribution of single nucleotide polymorphisms within FCRL3 and MAP3K7IP2 to the pathogenesis of Graves' disease." in: The Journal of clinical endocrinology and metabolism, Vol. 91, Issue 3, pp. 1056-61, (2006) (PubMed).
: "Two terms--one meaning: the conundrum of contemporary nomenclature in autism." in: Journal of child and adolescent psychiatric nursing : official publication of the Association of Child and Adolescent Psychiatric Nurses, Inc, Vol. 19, Issue 3, pp. 137-44, (2006) (PubMed).
Synonyms and alternative names related to TAB2
TGF-beta activated kinase 1/MAP3K7 binding protein 2 (TAB2), TGF-beta activated kinase 1/MAP3K7 binding protein 2 (Tab2), TGF-beta activated kinase 1/MAP3K7 binding protein 2 (tab2), 1110030N06Rik, A530078N03Rik, CHTD2, MAP3K7IP2, Map3k7ip2, map3k7ip2, mKIAA0733, zgc:77446Protein level used designations for TAB2
- TGF-beta activated kinase 1/MAP3K7 binding protein 2
- mitogen-activated protein kinase kinase kinase 7-interacting protein 2-like
- TAB-2
- TAK1-binding protein 2
- TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
- TGF-beta-activated kinase 1-binding protein 2
- mitogen-activated protein kinase kinase kinase 7-interacting protein 2
- mitogen-activated protein kinase kinase kinase 7 interacting protein 2
- Tak1 binding protein 2
- mitogen activated protein kinase kinase kinase 7 interacting protein 2
- mitogen-activated protein kinase kinase kinase 7-interacting protein 2 homolog
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