SYVN1 Products
(Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1))
Categories
This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. Sequence analysis identified two transcript variants that encode different isoforms. [provided by RefSeq, May 2011].
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Featured SYVN1 Categories
SYVN1 Antibodies
High quality antibodies with extensive validation data.
SYVN1 ELISA Kits
Reliable ELISA kits for a wide range of species.
SYVN1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SYVN1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p), IF
Validations
- (12)
- (6)
Cat. No.
ABIN388980
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF
Validations
- (10)
Cat. No.
ABIN3029082
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, ELISA, FACS, IF
Validations
- (4)
Cat. No.
ABIN1590085
Quantity
100 μg
Datasheet
Datasheet
Recommended SYVN1 ELISA Kits
Recommended SYVN1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322028
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322026
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2733142
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our SYVN1 products
: "Membralin deficiency dysregulates astrocytic glutamate homeostasis leading to ALS-like impairment." in: The Journal of clinical investigation, Vol. 129, Issue 8, pp. 3103-3120, (2019) (PubMed).: "IRE1α RNase-dependent lipid homeostasis promotes survival in Myc-transformed cancers." in: The Journal of clinical investigation, Vol. 128, Issue 4, pp. 1300-1316, (2018) (PubMed).
: "Characterization of protein complexes of the endoplasmic reticulum-associated degradation E3 ubiquitin ligase Hrd1." in: The Journal of biological chemistry, Vol. 292, Issue 22, pp. 9104-9116, (2017) (PubMed).
: "Familial prion protein mutants inhibit Hrd1-mediated retrotranslocation of misfolded proteins by depleting misfolded protein sensor BiP." in: Human molecular genetics, Vol. 25, Issue 5, pp. 976-88, (2016) (PubMed).
: "Grp94 Protein Delivers γ-Aminobutyric Acid Type A (GABAA) Receptors to Hrd1 Protein-mediated Endoplasmic Reticulum-associated Degradation." in: The Journal of biological chemistry, Vol. 291, Issue 18, pp. 9526-39, (2016) (PubMed).
: "Experimental study of the protective effects of SYVN1 against diabetic retinopathy." in: Scientific reports, Vol. 5, pp. 14036, (2016) (PubMed).
: "Acute ER stress regulates amyloid precursor protein processing through ubiquitin-dependent degradation." in: Scientific reports, Vol. 5, pp. 8805, (2015) (PubMed).
: "IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation." in: Nature cell biology, Vol. 17, Issue 12, pp. 1546-55, (2015) (PubMed).
: "TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 31, pp. 11425-30, (2014) (PubMed).
: "Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 5, pp. E582-91, (2014) (PubMed).
Synonyms and alternative names related to SYVN1
synoviolin 1 (SYVN1), synoviolin 1 (syvn1), synovial apoptosis inhibitor 1, synoviolin (Syvn1), synoviolin 1 (Syvn1), synoviolin 1 S homeolog (syvn1.S), synovial apoptosis inhibitor 1, synoviolin (syvn1), 1200010C09Rik, AW211966, C85322, D530017H19Rik, DER3, HRD1, hrd1, Hrd1, RGD1310488, syvn1, syvn1-a, syvn1-b, wu:fk91f10, zgc:55735, zgc:77108Protein level used designations for SYVN1
- E3 ubiquitin-protein ligase synoviolin
- HMG-coA reductase degradation 1 homolog
- synovial apoptosis inhibitor 1, synoviolin
- synoviolin 1
- HRD1 protein
- LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase synoviolin
- E3 ubiquitin-protein ligase synoviolin B
- RING-type E3 ubiquitin transferase synoviolin B
- Synovial apoptosis inhibitor 1-B
- synovial apoptosis inhibitor 1-B
- RING-type E3 ubiquitin transferase synoviolin
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