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SYNE2 Products

(Spectrin Repeat Containing, Nuclear Envelope 2 (SYNE2))
The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].

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Featured SYNE2 Categories

SYNE2 Antibodies

High quality antibodies with extensive validation data.

SYNE2 ELISA Kits

Reliable ELISA kits for a wide range of species.

SYNE2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SYNE2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB, IHC (p), ICC, IHC (fro)
Validations
  • (7)
Cat. No. ABIN7436189
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IF
Validations
  • (3)
Cat. No. ABIN565028
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7161170
Quantity 100 μg
Datasheet Datasheet

Recommended SYNE2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959660
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6209116
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5657231
Quantity 96 tests
Datasheet Datasheet

Recommended SYNE2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321987
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7398707
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2727102
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our SYNE2 products

Brody, Vanhoutte, Bakshi, Liu, Correll, Sargent, Molkentin: "Disruption of valosin-containing protein activity causes cardiomyopathy and reveals pleiotropic functions in cardiac homeostasis." in: The Journal of biological chemistry, Vol. 294, Issue 22, pp. 8918-8929, (2019) (PubMed).

Maddox, Collin, Ikeda, Pratt, Ikeda, Johnson, Hurd, Shopland, Naggert, Chang, Krebs, Nishina: "A Mutation in Syne2 Causes Early Retinal Defects in Photoreceptors, Secondary Neurons, and Müller Glia." in: Investigative ophthalmology & visual science, Vol. 56, Issue 6, pp. 3776-87, (2015) (PubMed).

Versaevel, Braquenier, Riaz, Grevesse, Lantoine, Gabriele: "Super-resolution microscopy reveals LINC complex recruitment at nuclear indentation sites." in: Scientific reports, Vol. 4, pp. 7362, (2014) (PubMed).

Neumann, Schneider, Daugherty, Gottardi, Eming, Beijer, Noegel, Karakesisoglou: "Nesprin-2 interacts with {alpha}-catenin and regulates Wnt signaling at the nuclear envelope." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34932-8, (2010) (PubMed).

Libotte, Zaim, Abraham, Padmakumar, Schneider, Lu, Munck, Hutchison, Wehnert, Fahrenkrog, Sauder, Aebi, Noegel, Karakesisoglou: "Lamin A/C-dependent localization of Nesprin-2, a giant scaffolder at the nuclear envelope." in: Molecular biology of the cell, Vol. 16, Issue 7, pp. 3411-24, (2005) (PubMed).

Zhen, Libotte, Munck, Noegel, Korenbaum: "NUANCE, a giant protein connecting the nucleus and actin cytoskeleton." in: Journal of cell science, Vol. 115, Issue Pt 15, pp. 3207-22, (2002) (PubMed).

Synonyms and alternative names related to SYNE2

spectrin repeat containing nuclear envelope protein 2 (SYNE2), spectrin repeat containing, nuclear envelope 2 (SYNE2), spectrin repeat containing, nuclear envelope 2 (syne2), spectrin repeat containing nuclear envelope protein 2 (syne2), spectrin repeat containing, nuclear envelope 2 (Syne2), spectrin repeat containing nuclear envelope protein 2 (Syne2), 6820443O06Rik, AW546258, D12Ertd777e, EDMD5, edmd5, mKIAA1011, Nesp2, Nesp2g, Nesprin-2, nesprin-2, NUA, nua, NUANCE, nuance, RGD1305248, SYNE-2, syne-2, SYNE2, TROPH

Protein level used designations for SYNE2

  • nesprin 2
  • nesprin-2
  • nuclear envelope spectrin repeat protein 2
  • nuclear envelope spectrin repeat-2
  • nucleus and actin connecting element protein
  • polytrophin
  • synaptic nuclear envelope protein 2
  • synaptic nuclei expressed gene 2
  • spectrin repeat containing, nuclear envelope 2
  • nesprin-2-like
  • nuance
  • synaptic nuclear envelope 2
  • LOW QUALITY PROTEIN: nesprin-2
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