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SYNCRIP Products

(Synaptotagmin Binding, Cytoplasmic RNA Interacting Protein (SYNCRIP))

Categories

This gene encodes a member of the cellular heterogeneous nuclear ribonucleoprotein (hnRNP) family. hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA) and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. The encoded protein plays a role in multiple aspects of mRNA maturation and is associated with several multiprotein complexes including the apoB RNA editing-complex and survival of motor neurons (SMN) complex. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 20. [provided by RefSeq, Dec 2011].

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Featured SYNCRIP Categories

SYNCRIP Antibodies

High quality antibodies with extensive validation data.

SYNCRIP ELISA Kits

Reliable ELISA kits for a wide range of species.

SYNCRIP Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SYNCRIP Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (5)
Cat. No. ABIN6148764
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (4)
Cat. No. ABIN7263205
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7155134
Quantity 100 μg
Datasheet Datasheet

Recommended SYNCRIP ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648147
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1743212
Quantity 96 tests
Datasheet Datasheet
Reactivity Sheep
Analytical Method
Validations
Cat. No. ABIN1774117
Quantity 96 tests
Datasheet Datasheet

Recommended SYNCRIP Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1790354
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321982
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7479304
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our SYNCRIP products

Ting, Wen, Liu, Hsieh-Li, Li, Lin-Chao: "The spinal muscular atrophy disease protein SMN is linked to the Golgi network." in: PLoS ONE, Vol. 7, Issue 12, pp. e51826, (2013) (PubMed).

Groen, Fumoto, Blokhuis, Engelen-Lee, Zhou, van den Heuvel, Koppers, van Diggelen, van Heest, Demmers, Kirby, Shaw, Aronica, Spliet, Veldink, van den Berg, Pasterkamp: "ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN." in: Human molecular genetics, Vol. 22, Issue 18, pp. 3690-704, (2013) (PubMed).

Katoh, Okamoto, Fukuhara, Kambara, Morita, Mori, Kamitani, Matsuura: "Japanese encephalitis virus core protein inhibits stress granule formation through an interaction with Caprin-1 and facilitates viral propagation." in: Journal of virology, Vol. 87, Issue 1, pp. 489-502, (2012) (PubMed).

Peddigari, Li, Rabe, Martin: "hnRNPL and nucleolin bind LINE-1 RNA and function as host factors to modulate retrotransposition." in: Nucleic acids research, Vol. 41, Issue 1, pp. 575-85, (2012) (PubMed).

Evans, Peddigari, Chaurasiya, Williams, Martin: "Paired mutations abolish and restore the balanced annealing and melting activities of ORF1p that are required for LINE-1 retrotransposition." in: Nucleic acids research, Vol. 39, Issue 13, pp. 5611-21, (2011) (PubMed).

Krüger, Kratchmarova, Blagoev, Tseng, Kahn, Mann: "Dissection of the insulin signaling pathway via quantitative phosphoproteomics." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 7, pp. 2451-6, (2008) (PubMed).

Fu, Collins: "Purification of human telomerase complexes identifies factors involved in telomerase biogenesis and telomere length regulation." in: Molecular cell, Vol. 28, Issue 5, pp. 773-85, (2007) (PubMed).

Van Herreweghe, Egloff, Goiffon, Jády, Froment, Monsarrat, Kiss: "Dynamic remodelling of human 7SK snRNP controls the nuclear level of active P-TEFb." in: The EMBO journal, Vol. 26, Issue 15, pp. 3570-80, (2007) (PubMed).

Hogg, Collins: "RNA-based affinity purification reveals 7SK RNPs with distinct composition and regulation." in: RNA (New York, N.Y.), Vol. 13, Issue 6, pp. 868-80, (2007) (PubMed).

Mourelatos, Abel, Yong, Kataoka, Dreyfuss: "SMN interacts with a novel family of hnRNP and spliceosomal proteins." in: The EMBO journal, Vol. 20, Issue 19, pp. 5443-52, (2001) (PubMed).

Synonyms and alternative names related to SYNCRIP

synaptotagmin binding cytoplasmic RNA interacting protein (SYNCRIP), synaptotagmin binding, cytoplasmic RNA interacting protein (Syncrip), synaptotagmin binding, cytoplasmic RNA interacting protein (syncrip), synaptotagmin binding cytoplasmic RNA interacting protein S homeolog (syncrip.S), synaptotagmin binding cytoplasmic RNA interacting protein (syncrip), synaptotagmin binding cytoplasmic RNA interacting protein (Syncrip), 2610109K23Rik, 4632417O19Rik, GRY-RBP, gry-rbp, GRYRBP, hnRNP-Q, HNRNPQ, HNRPQ1, hnrpq1, NSAP1, Nsap1, nsap1, Nsap1l, PP68, pp68, rp1-3j17.2, SYNCRIP, wu:fe02c03, wu:fe47h09

Protein level used designations for SYNCRIP

  • NS1-associated protein 1
  • glycine- and tyrosine-rich RNA-binding protein
  • heterogeneous nuclear ribonucleoprotein Q
  • RRM RNA binding protein GRY-RBP
  • hnRNP Q
  • hnRNP-Q
  • synaptotagmin-binding, cytoplasmic RNA-interacting protein
  • liver regeneration-related protein LRRG077
  • synaptotagmin binding, cytoplasmic RNA interacting protein
  • heterogeneous nuclear ribonucleoprotein Q-like
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