Synaptotagmin Products
(Synaptotagmin (SYT))
Categories
May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner\; these are neurexins, syntaxin and AP2 (By similarity).
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Featured Synaptotagmin Categories
Synaptotagmin Antibodies
High quality antibodies with extensive validation data.
Recommended Synaptotagmin Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (5)
Cat. No.
ABIN754888
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (4)
Cat. No.
ABIN6256502
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (4)
Cat. No.
ABIN6256263
Quantity
100 μL
Datasheet
Datasheet
Recommended Synaptotagmin ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380087
Quantity
2 x 96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380088
Quantity
2 x 96 tests
Datasheet
Datasheet
Latest Publications for our Synaptotagmin products
: "Nerve growth factor-dependent sorting of synaptotagmin IV protein to mature dense-core vesicles that undergo calcium-dependent exocytosis in PC12 cells." in: The Journal of biological chemistry, Vol. 278, Issue 5, pp. 3220-6, (2003) (PubMed).: "The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility." in: Cell, Vol. 111, Issue 2, pp. 209-18, (2002) (PubMed).
: "Synaptotagmin IX regulates Ca2+-dependent secretion in PC12 cells." in: The Journal of biological chemistry, Vol. 277, Issue 7, pp. 4601-4, (2002) (PubMed).
: "Botulinum neurotoxin A activity is dependent upon the presence of specific gangliosides in neuroblastoma cells expressing synaptotagmin I." in: The Journal of biological chemistry, Vol. 277, Issue 36, pp. 32815-9, (2002) (PubMed).
: "SNAREs in mammalian sperm: possible implications for fertilization." in: Developmental biology, Vol. 223, Issue 1, pp. 54-69, (2000) (PubMed).
: "Synaptotagmin IV is present at the Golgi and distal parts of neurites." in: Journal of neurochemistry, Vol. 74, Issue 2, pp. 518-26, (2000) (PubMed).
: "High-efficiency Semliki Forest virus-mediated transduction in bovine adrenal chromaffin cells." in: The Biochemical journal, Vol. 342 Pt 3, pp. 497-501, (1999) (PubMed).
: "Membrane trafficking in the presynaptic nerve terminal." in: Neuron, Vol. 14, Issue 5, pp. 893-7, (1995) (PubMed).
: "Comparison of immunolocalization patterns for the synaptic vesicle proteins p65 and synapsin I in macaque monkey retina." in: Synapse (New York, N.Y.), Vol. 14, Issue 4, pp. 268-82, (1994) (PubMed).
: "Structural and functional conservation of synaptotagmin (p65) in Drosophila and humans." in: The Journal of biological chemistry, Vol. 266, Issue 1, pp. 615-22, (1991) (PubMed).
Synonyms and alternative names related to Synaptotagmin
SyNapTotagmin (snt-5), SyNapTotagmin (snt-6), SyNapTotagmin (snt-3), synaptotagmin (Syt), synaptotagmin 1 (Syt1), synaptotagmin 1 (SYT1), DKFZP459P193, GB20036, SYT1, Syti, SytIProtein level used designations for Synaptotagmin
- SyNapTotagmin family member (snt-5)
- SyNapTotagmin family member (snt-6)
- SyNapTotagmin family member (snt-3)
- synaptotagmin
- synaptotagmin I
- synaptotagmin-1
- DKFZP459P193 protein
- Synaptotagmin I
- Synaptotagmin-1
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