Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

SYK Products

(Spleen tyrosine Kinase (SYK))

Categories

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured SYK Categories

SYK Antibodies

High quality antibodies with extensive validation data.

SYK ELISA Kits

Reliable ELISA kits for a wide range of species.

SYK Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SYK Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IP, IHC (p), ICC
Validations
  • (4)
  • (6)
Cat. No. ABIN94475
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (12)
Cat. No. ABIN6256708
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (13)
Cat. No. ABIN6255944
Quantity 100 μL
Datasheet Datasheet

Recommended SYK ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
  • (3)
Cat. No. ABIN1981728
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970412
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959691
Quantity 96 tests
Datasheet Datasheet

Recommended SYK Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321970
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321972
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN5509166
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our SYK products

Hasan, Rahman, Sebo, Osicka: "Distinct Spatiotemporal Distribution of Bacterial Toxin-Produced Cellular cAMP Differentially Inhibits Opsonophagocytic Signaling." in: Toxins, Vol. 11, Issue 6, (2020) (PubMed).

Zhang, Kang, Liu, Gu, Song, Li, Wang, Yao, Li, Li, Wang, Li, Mao: "Flavanomarein inhibits high glucose-stimulated epithelial-mesenchymal transition in HK-2 cells via targeting spleen tyrosine kinase." in: Scientific reports, Vol. 10, Issue 1, pp. 439, (2020) (PubMed).

Schweig, Yao, Beaulieu-Abdelahad, Ait-Ghezala, Mouzon, Crawford, Mullan, Paris: "Alzheimer's disease pathological lesions activate the spleen tyrosine kinase." in: Acta neuropathologica communications, Vol. 5, Issue 1, pp. 69, (2018) (PubMed).

Köhler, Fuhr, Dinekov: "Distribution of spleen tyrosine kinase and tau phosphorylated at tyrosine 18 in a mouse model of tauopathy and in the human hippocampus." in: Brain research, Vol. 1677, pp. 1-13, (2018) (PubMed).

Greenblatt, Park, Oh, Kim, Shin, Lee, Lee, Singh, Lee, Hu, Xiao, Charles, Penninger, Lotinun, Baron, Ghosh, Shim: "CHMP5 controls bone turnover rates by dampening NF-?B activity in osteoclasts." in: The Journal of experimental medicine, Vol. 212, Issue 8, pp. 1283-301, (2015) (PubMed).

Nishikawa, Takahashi, Nakamori, Hosomi, Maruyama, Miyazaki, Izumi, Matsumoto: "The identification of raft-derived tau-associated vesicles that are incorporated into immature tangles and paired helical filaments." in: Neuropathology and applied neurobiology, (2015) (PubMed).

Le Huu, Kimura, Date, Hamaguchi, Hasegawa, Hau, Fujimoto, Takehara, Matsushita: "Blockade of Syk ameliorates the development of murine sclerodermatous chronic graft-versus-host disease." in: Journal of dermatological science, Vol. 74, Issue 3, pp. 214-21, (2014) (PubMed).

Paris, Ait-Ghezala, Bachmeier, Laco, Beaulieu-Abdelahad, Lin, Jin, Crawford, Mullan: "The spleen tyrosine kinase (Syk) regulates Alzheimer amyloid-β production and Tau hyperphosphorylation." in: The Journal of biological chemistry, Vol. 289, Issue 49, pp. 33927-44, (2014) (PubMed).

Satoh, Tabunoki, Ishida, Yagishita, Jinnai, Futamura, Kobayashi, Toyoshima, Yoshioka, Enomoto, Arai, Saito, Arima: "Phosphorylated Syk expression is enhanced in Nasu-Hakola disease brains." in: Neuropathology : official journal of the Japanese Society of Neuropathology, Vol. 32, Issue 2, pp. 149-57, (2012) (PubMed).

Coopman, Mueller: "The Syk tyrosine kinase: a new negative regulator in tumor growth and progression." in: Cancer letters, Vol. 241, Issue 2, pp. 159-73, (2006) (PubMed).

Synonyms and alternative names related to SYK

spleen associated tyrosine kinase (syk), spleen associated tyrosine kinase (SYK), spleen tyrosine kinase (Syk), spleen associated tyrosine kinase (Syk), p72-Syk, p72syk, Sykb

Protein level used designations for SYK

  • Tyrosine-protein kinase SYK
  • tyrosine-protein kinase SYK
  • protein-tyrosine kinase
You are here:
Support