SYK Products
(Spleen tyrosine Kinase (SYK))
Categories
This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].
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Featured SYK Categories
SYK Antibodies
High quality antibodies with extensive validation data.
SYK ELISA Kits
Reliable ELISA kits for a wide range of species.
SYK Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SYK Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IP, IHC (p), ICC
Validations
- (4)
- (6)
Cat. No.
ABIN94475
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human, Monkey, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (12)
Cat. No.
ABIN6256708
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Monkey, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (13)
Cat. No.
ABIN6255944
Quantity
100 μL
Datasheet
Datasheet
Recommended SYK ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (3)
Cat. No.
ABIN1981728
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970412
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959691
Quantity
96 tests
Datasheet
Datasheet
Recommended SYK Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321970
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321972
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5509166
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our SYK products
: "Distinct Spatiotemporal Distribution of Bacterial Toxin-Produced Cellular cAMP Differentially Inhibits Opsonophagocytic Signaling." in: Toxins, Vol. 11, Issue 6, (2020) (PubMed).: "Flavanomarein inhibits high glucose-stimulated epithelial-mesenchymal transition in HK-2 cells via targeting spleen tyrosine kinase." in: Scientific reports, Vol. 10, Issue 1, pp. 439, (2020) (PubMed).
: "Alzheimer's disease pathological lesions activate the spleen tyrosine kinase." in: Acta neuropathologica communications, Vol. 5, Issue 1, pp. 69, (2018) (PubMed).
: "Distribution of spleen tyrosine kinase and tau phosphorylated at tyrosine 18 in a mouse model of tauopathy and in the human hippocampus." in: Brain research, Vol. 1677, pp. 1-13, (2018) (PubMed).
: "CHMP5 controls bone turnover rates by dampening NF-?B activity in osteoclasts." in: The Journal of experimental medicine, Vol. 212, Issue 8, pp. 1283-301, (2015) (PubMed).
: "The identification of raft-derived tau-associated vesicles that are incorporated into immature tangles and paired helical filaments." in: Neuropathology and applied neurobiology, (2015) (PubMed).
: "Blockade of Syk ameliorates the development of murine sclerodermatous chronic graft-versus-host disease." in: Journal of dermatological science, Vol. 74, Issue 3, pp. 214-21, (2014) (PubMed).
: "The spleen tyrosine kinase (Syk) regulates Alzheimer amyloid-β production and Tau hyperphosphorylation." in: The Journal of biological chemistry, Vol. 289, Issue 49, pp. 33927-44, (2014) (PubMed).
: "Phosphorylated Syk expression is enhanced in Nasu-Hakola disease brains." in: Neuropathology : official journal of the Japanese Society of Neuropathology, Vol. 32, Issue 2, pp. 149-57, (2012) (PubMed).
: "The Syk tyrosine kinase: a new negative regulator in tumor growth and progression." in: Cancer letters, Vol. 241, Issue 2, pp. 159-73, (2006) (PubMed).
Synonyms and alternative names related to SYK
spleen associated tyrosine kinase (syk), spleen associated tyrosine kinase (SYK), spleen tyrosine kinase (Syk), spleen associated tyrosine kinase (Syk), p72-Syk, p72syk, SykbProtein level used designations for SYK
- Tyrosine-protein kinase SYK
- tyrosine-protein kinase SYK
- protein-tyrosine kinase
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