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SYCP1 Products

(Synaptonemal Complex Protein 1 (SYCP1))

Categories

Preferentially catalyzes the dephosphorylation of 'Ser- 5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.

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Featured SYCP1 Categories

SYCP1 Antibodies

High quality antibodies with extensive validation data.

SYCP1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SYCP1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse, Rat
Application IHC, IF
Validations
  • (4)
Cat. No. ABIN7075786
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN6257491
Quantity 100 μL
Datasheet Datasheet
Reactivity Guinea Pig, Human, Mouse, Rat
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN6748640
Quantity 100 μL
Datasheet Datasheet

Recommended SYCP1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3095752
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3135525
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2733024
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our SYCP1 products

Tian, Billings, Petkov: "CXXC1 is not essential for normal DNA double-strand break formation and meiotic recombination in mouse." in: PLoS genetics, Vol. 14, Issue 10, pp. e1007657, (2019) (PubMed).

Abreu, Prakash, Romanienko, Roig, Keeney, Jasin: "Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination." in: Nature communications, Vol. 9, Issue 1, pp. 3961, (2019) (PubMed).

Huang, Kaufman, Ryan, Romin, Huryn, Bains, Manova-Todorova, Morris, Hunnicutt, Adelman, Petrini, Ramanathan, Singh: "Mouse DCUN1D1 (SCCRO) is required for spermatogenetic individualization." in: PLoS ONE, Vol. 14, Issue 1, pp. e0209995, (2019) (PubMed).

Eyster, Chuong, Lee, Pezza, Dawson: "The pericentromeric heterochromatin of homologous chromosomes remains associated after centromere pairing dissolves in mouse spermatocyte meiosis." in: Chromosoma, (2019) (PubMed).

Lam, Brick, Cheng, Pratto, Camerini-Otero: "Cell-type-specific genomics reveals histone modification dynamics in mammalian meiosis." in: Nature communications, Vol. 10, Issue 1, pp. 3821, (2019) (PubMed).

Hua, Wei, Liu, Zhang, Liu, Guo, Cui, Zhang, Guo, Li, Liu: "FBXO47 regulates telomere-inner nuclear envelope integration by stabilizing TRF2 during meiosis." in: Nucleic acids research, Vol. 47, Issue 22, pp. 11755-11770, (2019) (PubMed).

Wang, Tu, Liu, Liu, Kaldis, Chen, Li: "Dual roles of TRF1 in tethering telomeres to the nuclear envelope and protecting them from fusion during meiosis." in: Cell death and differentiation, Vol. 25, Issue 6, pp. 1174-1188, (2018) (PubMed).

Guiraldelli, Felberg, Almeida, Parikh, de Castro, Pezza: "SHOC1 is a ERCC4-(HhH)2-like protein, integral to the formation of crossover recombination intermediates during mammalian meiosis." in: PLoS genetics, Vol. 14, Issue 5, pp. e1007381, (2018) (PubMed).

Tsang, Gantchev, Netchiporouk, Moreau, Ghazawi, Glassman, Sasseville, Litvinov: "A study of meiomitosis and novel pathways of genomic instability in cutaneous T-cell lymphomas (CTCL)." in: Oncotarget, Vol. 9, Issue 102, pp. 37647-37661, (2018) (PubMed).

Dai, Voloshin, Potapova, Camerini-Otero: "Meiotic Knockdown and Complementation Reveals Essential Role of RAD51 in Mouse Spermatogenesis." in: Cell reports, Vol. 18, Issue 6, pp. 1383-1394, (2017) (PubMed).

Synonyms and alternative names related to SYCP1

synaptonemal complex protein 1 (SYCP1), synaptonemal complex protein 1 (sycp1), Myosin heavy chain-related protein (ZYP1a), synaptonemal complex protein 1 (Sycp1), CT8, HOM-TES-14, SCP-1, SCP1, SYCP1, sycp1, syn1, T16E15.12, T16E15_12, ZYP1

Protein level used designations for SYCP1

  • SCP-1
  • cancer/testis antigen 8
  • synaptonemal complex protein 1
  • synaptonemal complex protein 1-like
  • A coiled-coil related protein specific for synapsed regions of meiotic prophase chromosomes
  • Meiotic chromosome synaptic protein
  • LOW QUALITY PROTEIN: synaptonemal complex protein 1
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