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SWAP70 Products

(SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))

Categories

Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity).

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Featured SWAP70 Categories

SWAP70 Antibodies

High quality antibodies with extensive validation data.

SWAP70 ELISA Kits

Reliable ELISA kits for a wide range of species.

SWAP70 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SWAP70 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (6)
Cat. No. ABIN524958
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (8)
Cat. No. ABIN565005
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN7270654
Quantity 100 μL
Datasheet Datasheet

Recommended SWAP70 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970499
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6232504
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1160275
Quantity 96 tests
Datasheet Datasheet

Recommended SWAP70 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321955
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321957
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3095696
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SWAP70 products

Baranov, Revelo, Dingjan, Maraspini, Ter Beest, Honigmann, van den Bogaart: "SWAP70 Organizes the Actin Cytoskeleton and Is Essential for Phagocytosis." in: Cell reports, Vol. 17, Issue 6, pp. 1518-1531, (2016) (PubMed).

Chang, Shu, Lai, Ching-Yu, Chuu, Morishita, Ichikawa, Jessberger, Fukui: "SWAP-70 contributes to spontaneous transformation of mouse embryo fibroblasts." in: Experimental cell research, (2015) (PubMed).

Kegel, Jaegle, Driegen, Aunin, Leslie, Fukata, Watanabe, Fukata, Meijer: "Functional phylogenetic analysis of LGI proteins identifies an interaction motif crucial for myelination." in: Development (Cambridge, England), Vol. 141, Issue 8, pp. 1749-56, (2014) (PubMed).

Cohen, Jun, Bears, Barrera, Alonso, Engelman, DiMaio: "Mapping the homodimer interface of an optimized, artificial, transmembrane protein activator of the human erythropoietin receptor." in: PLoS ONE, Vol. 9, Issue 4, pp. e95593, (2014) (PubMed).

Rosati, Krebs, Liu: "Emissions from cooking microwave popcorn." in: Critical reviews in food science and nutrition, Vol. 47, Issue 8, pp. 701-9, (2007) (PubMed).

Pearce, Angeli, Randolph, Junt, von Andrian, Schnittler, Jessberger: "Signaling protein SWAP-70 is required for efficient B cell homing to lymphoid organs." in: Nature immunology, Vol. 7, Issue 8, pp. 827-34, (2006) (PubMed).

Hilpelä, Oberbanscheidt, Hahne, Hund, Kalhammer, Small, Bähler: "SWAP-70 identifies a transitional subset of actin filaments in motile cells." in: Molecular biology of the cell, Vol. 14, Issue 8, pp. 3242-53, (2003) (PubMed).

Rapalus, Minegishi, Lavoie, Cunningham-Rundles, Conley: "Analysis of SWAP-70 as a candidate gene for non-X-linked hyper IgM syndrome and common variable immunodeficiency." in: Clinical immunology (Orlando, Fla.), Vol. 101, Issue 3, pp. 270-5, (2001) (PubMed).

Masat, Caldwell, Armstrong, Khoshnevisan, Jessberger, Herndier, Wabl, Ferrick: "Association of SWAP-70 with the B cell antigen receptor complex." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 5, pp. 2180-4, (2000) (PubMed).

Synonyms and alternative names related to SWAP70

switching B-cell complex subunit SWAP70 (SWAP70), SWA-70 protein (Swap70), SWAP switching B-cell complex 70 (Swap70), SWAP switching B-cell complex 70kDa subunit (SWAP70), switching B-cell complex subunit SWAP70 (swap70), switching B-cell complex subunit SWAP70 (Swap70), switching B-cell complex subunit SWAP70a (swap70a), 70kDa, AV235546, HSPC321, SWAP-70, swap70b, zgc:63599

Protein level used designations for SWAP70

  • switch-associated protein 70
  • SWAP complex protein, 70 kDa
  • SWAP-70
  • SWA-70 protein
  • SWAP complex protein
  • SWAP-70 protein
  • SWAP switching B-cell complex 70kDa subunit
  • switch-associated protein 70-like
  • SWAP switching B-cell complex subunit 70
  • SWAP switching B-cell complex 70a subunit 70a
  • SWAP switching B-cell complex subunit 70a
  • uncharacterized protein LOC393645
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