SUV39H1 Products
(Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1))
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This gene is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression. [provided by RefSeq, Jul 2008].
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Featured SUV39H1 Categories
SUV39H1 Antibodies
High quality antibodies with extensive validation data.
SUV39H1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SUV39H1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Rat
Application
IHC, IF
Validations
- (6)
Cat. No.
ABIN7075770
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7155525
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN6265384
Quantity
100 μL
Datasheet
Datasheet
Recommended SUV39H1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6207821
Quantity
96 tests
Datasheet
Datasheet
Recommended SUV39H1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125258
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321937
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321936
Quantity
25 μg
Datasheet
Datasheet
Latest Publications for our SUV39H1 products
: "Sirt7 inhibits Sirt1-mediated activation of Suv39h1." in: Cell cycle (Georgetown, Tex.), Vol. 17, Issue 12, pp. 1403-1412, (2018) (PubMed).: "Global histone modification profiling reveals the epigenomic dynamics during malignant transformation in a four-stage breast cancer model." in: Clinical epigenetics, Vol. 8, pp. 34, (2016) (PubMed).
: "Role of histone lysine methyltransferases SUV39H1 and SETDB1 in gliomagenesis: modulation of cell proliferation, migration, and colony formation." in: Neuromolecular medicine, Vol. 16, Issue 1, pp. 70-82, (2014) (PubMed).
: "A role for SUV39H1-mediated H3K9 trimethylation in the control of genome stability and senescence in WI38 human diploid lung fibroblasts." in: Aging, Vol. 6, Issue 7, pp. 545-63, (2014) (PubMed).
: "SUV39H1 downregulation induces deheterochromatinization of satellite regions and senescence after exposure to ionizing radiation." in: Frontiers in genetics, Vol. 5, pp. 411, (2014) (PubMed).
: "High expressions of histone methylation- and phosphorylation-related proteins are associated with prognosis of oral squamous cell carcinoma in male population of Taiwan." in: Medical oncology (Northwood, London, England), Vol. 30, Issue 2, pp. 513, (2013) (PubMed).
: "Remodeling of ribosomal genes in somatic cells by Xenopus egg extract." in: Biochemical and biophysical research communications, Vol. 412, Issue 3, pp. 487-93, (2011) (PubMed).
: "Epigenetic regulation of surfactant protein A gene (SP-A) expression in fetal lung reveals a critical role for Suv39h methyltransferases during development and hypoxia." in: Molecular and cellular biology, Vol. 31, Issue 10, pp. 1949-58, (2011) (PubMed).
: "Activation of Hif1α by the prolylhydroxylase inhibitor dimethyoxalyglycine decreases radiosensitivity." in: PLoS ONE, Vol. 6, Issue 10, pp. e26064, (2011) (PubMed).
: "EVI-1 interacts with histone methyltransferases SUV39H1 and G9a for transcriptional repression and bone marrow immortalization." in: Leukemia, Vol. 24, Issue 1, pp. 81-8, (2010) (PubMed).
Synonyms and alternative names related to SUV39H1
suppressor of variegation 3-9 homolog 1 (SUV39H1), suppressor of variegation 3-9 homolog 1 (Drosophila) (Suv39h1), suppressor of variegation 3-9 homolog 1 L homeolog (suv39h1.L), suppressor of variegation 3-9 homolog 1a (suv39h1a), suppressor of variegation 3-9 homolog 1 (Suv39h1), suppressor of variegation 3-9 homolog 1b (suv39h1b), AI852103, AL022883, DXHXS7466e, fe02c04, fe47h06, H3-K9-HMTase 1, KMT1A, kmt1a, MG44, mIS6, RGD1565028, SUV39H, suv39h, suv39h1, wu:fb18a10, wu:fe02c04, wu:fe47h06, zgc:101027, zgc:136593Protein level used designations for SUV39H1
- Su(var)3-9 homolog 1
- histone H3-K9 methyltransferase 1
- histone-lysine N-methyltransferase SUV39H1
- histone-lysine N-methyltransferase, H3 lysine-9 specific 1
- lysine N-methyltransferase 1A
- position-effect variegation 3-9 homolog
- H3-K9-HMTase 1
- Suv39h histone methyltransferase
- su(var)3-9 homolog 1
- histone-lysine N-methyltransferase SUV39H1-A
- su(var)3-9 homolog 1-A
- suppressor of variegation 3-9 homolog 1
- suppressor of variegation 3-9 homolog 1-A
- suppressor of variegation 3-9-like 1a
- LOW QUALITY PROTEIN: histone-lysine N-methyltransferase SUV39H1
- suppressor of variegation 3-9-like 1b homolog 1
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