Surfactant Protein C Products
(Surfactant Protein C (SFTPC))
Categories
This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.[provided by RefSeq, Feb 2010].
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Featured Surfactant Protein C Categories
Surfactant Protein C Antibodies
High quality antibodies with extensive validation data.
Surfactant Protein C ELISA Kits
Reliable ELISA kits for a wide range of species.
Surfactant Protein C Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Surfactant Protein C Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (6)
Cat. No.
ABIN7259843
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (10)
Cat. No.
ABIN3015598
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7443620
Quantity
100 μL
Datasheet
Datasheet
Recommended Surfactant Protein C ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
Cat. No.
ABIN6720570
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (8)
- (1)
Cat. No.
ABIN6959782
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6959783
Quantity
96 tests
Datasheet
Datasheet
Recommended Surfactant Protein C Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319780
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7394438
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7402970
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Surfactant Protein C products
: "Chronic lung injury and impaired pulmonary function in a mouse model of acid ceramidase deficiency." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 314, Issue 3, pp. L406-L420, (2019) (PubMed).: "Efficient Differentiation of Mouse Induced Pluripotent Stem Cells into Alveolar Epithelium Type II with a BRD4 Inhibitor." in: Stem cells international, Vol. 2019, pp. 1271682, (2019) (PubMed).
: "Serum Surfactant Protein Levels in Patients Admitted to the Hospital with Acute COPD Exacerbation." in: Lung, Vol. 196, Issue 2, pp. 201-205, (2019) (PubMed).
: "Adipose Tissue-Derived Stem Cells Have the Ability to Differentiate into Alveolar Epithelial Cells and Ameliorate Lung Injury Caused by Elastase-Induced Emphysema in Mice." in: Stem cells international, Vol. 2019, pp. 5179172, (2019) (PubMed).
: "Effects and molecular mechanisms of intrauterine infection/inflammation on lung development." in: Respiratory research, Vol. 19, Issue 1, pp. 93, (2018) (PubMed).
: "Correlations of Ventricular Enlargement with Rheologically Active Surfactant Proteins in Cerebrospinal Fluid." in: Frontiers in aging neuroscience, Vol. 8, pp. 324, (2017) (PubMed).
: "Derivation of therapeutic lung spheroid cells from minimally invasive transbronchial pulmonary biopsies." in: Respiratory research, Vol. 18, Issue 1, pp. 132, (2017) (PubMed).
: "Serum Levels of Surfactant Proteins in Patients with Combined Pulmonary Fibrosis and Emphysema (CPFE)." in: PLoS ONE, Vol. 11, Issue 6, pp. e0157789, (2016) (PubMed).
: "SB203580 inhibits epithelial-mesenchymal transition and pulmonary fibrosis in a rat silicosis model." in: Toxicology letters, Vol. 259, pp. 28-34, (2016) (PubMed).
: "The Cerebral Surfactant System and Its Alteration in Hydrocephalic Conditions." in: PLoS ONE, Vol. 11, Issue 9, pp. e0160680, (2016) (PubMed).
Synonyms and alternative names related to Surfactant Protein C
surfactant protein C (SFTPC), surfactant, pulmonary-associated protein C S homeolog (sftpc.S), surfactant, pulmonary-associated protein C (sftpc), surfactant associated protein C (Sftpc), surfactant protein C (Sftpc), Bricd6, BRICD6, pro-SpC, psp-c, PSP-C, Sftp-2, sftp2, Sftp2, SFTP2, SFTPC, SMDP2, SP-C, SP5, SPC, xSP-CProtein level used designations for Surfactant Protein C
- surfactant protein C
- surfactant, pulmonary-associated protein C
- pulmonary surfactant-associated protein C
- pulmonary surfactant-associated proteolipid SPL(Val)
- BRICHOS domain containing 6
- SP5
- pulmonary surfactant apoprotein-2 SP-C
- SP-C
- Surfactant pulmonary-associated protein C
- Surfactant, pulmonary-associated protein C
- surfactant associated protein C
- type I SP-C
- type II SP-C
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