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Supervillin Products

(Supervillin (SVIL))
This gene encodes a bipartite protein with distinct amino- and carboxy-terminal domains. The amino-terminus contains nuclear localization signals and the carboxy-terminus contains numerous consecutive sequences with extensive similarity to proteins in the gelsolin family of actin-binding proteins, which cap, nucleate, and/or sever actin filaments. The gene product is tightly associated with both actin filaments and plasma membranes, suggesting a role as a high-affinity link between the actin cytoskeleton and the membrane. The encoded protein appears to aid in both myosin II assembly during cell spreading and disassembly of focal adhesions. Two transcript variants encoding different isoforms of supervillin have been described. [provided by RefSeq, Jul 2008].

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Featured Supervillin Categories

Supervillin Antibodies

High quality antibodies with extensive validation data.

Supervillin ELISA Kits

Reliable ELISA kits for a wide range of species.

Supervillin Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Supervillin Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (3)
Cat. No. ABIN563071
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7435214
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (1)
Cat. No. ABIN7427723
Quantity 100 μL
Datasheet Datasheet

Recommended Supervillin ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1160133
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1160134
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1160132
Quantity 96 tests
Datasheet Datasheet

Recommended Supervillin Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321952
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7400891
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7396883
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Supervillin products

Hiruma, Kamasaki, Otomo, Nemoto, Uehara: "Dynamics and function of ERM proteins during cytokinesis in human cells." in: FEBS letters, Vol. 591, Issue 20, pp. 3296-3309, (2017) (PubMed).

Synonyms and alternative names related to Supervillin

supervillin a (svila), supervillin (SVIL), supervillin (LOC5577073), supervillin (CpipJ_CPIJ003700), supervillin, putative (Smp_148580), supervillin (svil), supervillin (Svil), AU024053, B430302E16Rik, DKFZp468F0819, sb:cb867, svil, SVIL, wu:fd05a09

Protein level used designations for Supervillin

  • supervillin
  • zmp:0000000648
  • archvillin
  • membrane-associated F-actin binding protein p205
  • p205/p250
  • supervillin muscle-specific isoform
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