SUN2 Products
(Sad1 and UNC84 Domain Containing 2 (SUN2))
Categories
SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1\; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).[supplied by OMIM, Nov 2010].
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Featured SUN2 Categories
SUN2 Antibodies
High quality antibodies with extensive validation data.
SUN2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SUN2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (8)
Cat. No.
ABIN7075502
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
Cat. No.
ABIN7270136
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7170975
Quantity
100 μg
Datasheet
Datasheet
Recommended SUN2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324663
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3118899
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3136192
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our SUN2 products
: "Samp1 is a component of TAN lines and is required for nuclear movement." in: Journal of cell science, Vol. 125, Issue Pt 5, pp. 1099-105, (2012) (PubMed).: "Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes." in: The Journal of biological chemistry, Vol. 285, Issue 5, pp. 3487-98, (2010) (PubMed).
Synonyms and alternative names related to SUN2
Sad1 and UNC84 domain containing 2 (SUN2), Sad1 and UNC84 domain containing 2 (Sun2), B230369L08Rik, C030011B15, RGD1563141, UNC84B, Unc84bProtein level used designations for SUN2
- SUN domain-containing protein 2
- Sad1 unc-84 domain protein 2
- nuclear envelope protein
- protein unc-84 homolog B
- rab5-interacting protein
- rab5IP
- sad1/unc-84 protein-like 2
- unc-84 homolog B
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