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STXBP5 Products

(Syntaxin Binding Protein 5 (Tomosyn) (STXBP5))

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Syntaxin 1 is a component of the 7S and 20S SNARE complexes which are involved in docking and fusion of synaptic vesicles with the presynaptic plasma membrane. This gene encodes a syntaxin 1 binding protein. In rat, a similar protein dissociates syntaxin 1 from the Munc18/n-Sec1/rbSec1 complex to form a 10S complex, an intermediate which can be converted to the 7S SNARE complex. Thus this protein is thought to be involved in neurotransmitter release by stimulating SNARE complex formation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

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Featured STXBP5 Categories

STXBP5 Antibodies

High quality antibodies with extensive validation data.

STXBP5 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended STXBP5 Antibodies

Product
Reactivity
Application
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Cat. No.
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Datasheet
Reactivity Human
Application ELISA, IF, IHC
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Cat. No. ABIN7171265
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Human, Mouse, Rat
Application WB, ICC
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  • (1)
  • (2)
Cat. No. ABIN1742382
Quantity 50 μg
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Reactivity Human
Application ELISA, WB
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  • (1)
Cat. No. ABIN566817
Quantity 50 μL
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Recommended STXBP5 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
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Cat. No. ABIN6233066
Quantity 96 tests
Datasheet Datasheet

Recommended STXBP5 Proteins

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Validations
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Source Wheat germ
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Cat. No. ABIN1321822
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
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Cat. No. ABIN3095727
Quantity 1 mg
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Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
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Cat. No. ABIN3136593
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Latest Publications for our STXBP5 products

Burgalossi, Jung, Meyer, Jockusch, Jahn, Taschenberger, OConnor, Nishiki, Takahashi, Brose, Rhee: "SNARE protein recycling by αSNAP and βSNAP supports synaptic vesicle priming." in: Neuron, Vol. 68, Issue 3, pp. 473-87, (2010) (PubMed).

Yokoyama, Shirataki, Sakisaka, Takai: "Three splicing variants of tomosyn and identification of their syntaxin-binding region." in: Biochemical and biophysical research communications, Vol. 256, Issue 1, pp. 218-22, (1999) (PubMed).

Fujita, Shirataki, Sakisaka, Asakura, Ohya, Kotani, Yokoyama, Nishioka, Matsuura, Mizoguchi, Scheller, Takai: "Tomosyn: a syntaxin-1-binding protein that forms a novel complex in the neurotransmitter release process." in: Neuron, Vol. 20, Issue 5, pp. 905-15, (1998) (PubMed).

Synonyms and alternative names related to STXBP5

syntaxin binding protein 5 (STXBP5), syntaxin binding protein 5 (tomosyn) (Stxbp5), syntaxin binding protein 5 (Stxbp5), 0710001E20Rik, 4930565N16Rik, AW742610, LGL3, LLGL3, mKIAA1006, Nbla04300

Protein level used designations for STXBP5

  • lethal(2) giant larvae protein homolog 3
  • putative protein product of Nbla04300
  • syntaxin-binding protein 5
  • tomosyn
  • tomosyn-1
  • tomosyn 1
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