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Streptolysin O Products

(Streptolysin O (SLO))

Categories

Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation (By similarity).

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Featured Streptolysin O Categories

Streptolysin O Antibodies

High quality antibodies with extensive validation data.

Streptolysin O Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Streptolysin O Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Streptococcus pyogenes
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN791623
Quantity 100 μL
Datasheet Datasheet

Recommended Streptolysin O ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rabbit
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN774025
Quantity 96 tests
Datasheet Datasheet

Recommended Streptolysin O Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Streptococcus pyogenes
Source Escherichia coli (E. coli)
Validations
  • (3)
  • (2)
Cat. No. ABIN2452205
Quantity 20 μg
Datasheet Datasheet
Reactivity Streptococcus pyogenes
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2017554
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN1543635
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Streptolysin O products

Maeda, Ide, Koike, Uchiyama, Kinoshita: "GPHR is a novel anion channel critical for acidification and functions of the Golgi apparatus." in: Nature cell biology, Vol. 10, Issue 10, pp. 1135-45, (2008) (PubMed).

Walev, Bhakdi, Hofmann, Djonder, Valeva, Aktories, Bhakdi: "Delivery of proteins into living cells by reversible membrane permeabilization with streptolysin-O." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 6, pp. 3185-90, (2001) (PubMed).

Palmer: "The family of thiol-activated, cholesterol-binding cytolysins." in: Toxicon : official journal of the International Society on Toxinology, Vol. 39, Issue 11, pp. 1681-9, (2001) (PubMed).

Synonyms and alternative names related to Streptolysin O

streptolysin O (slo), streptolysin O (M6_Spy0188), Streptolysin O (slo), Thiol-activated cytolysin (slo)

Protein level used designations for Streptolysin O

  • streptolysin O
  • Streptolysin O
  • Thiol-activated cytolysin
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